Art

J-GLOBAL ID：201802216960073926   Reference number：18A1027094

Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan

日本の脂肪酸酸化障害患者におけるベザフィブラート治療のオープンラベル臨床試験【JST・京大機械翻訳】

Author (28)： Yamada Kenji (Department of Pediatrics, Shimane University Faculty of Medicine, 89-1, En-ya-cho, Izumo, Shimane 693-8501, Japan) ,  Shiraishi Hideaki (Department of Pediatrics, Hokkaido University School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan) ,  Oki Eishin (Department of Pediatrics, Tsugaru General Hospital, 12-3, Iwaki-cho, Goshogawara, Aomori 037-0074, Japan) ,  Ishige Mika (Department of Pediatrics and Child Health, Nihon University School of Medicine, 1-6, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8309, Japan) ,  Fukao Toshiyuki (Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1, Yanagito, Gifu 501-1194, Japan) ,  Hamada Yusuke (Department of Pediatrics, Osaka University Faculty of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Hamada Yusuke (Department of Pediatrics, Osaka Hospital, Japan Community Healthcare Organization, 4-2-78, Fukushima, Fukushima-ku, Osaka 553-0003, Japan) ,  Sakai Norio (Department of Pediatrics, Osaka University Faculty of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Ochi Fumihiro (Department of Pediatrics, Yawatahama City General Hospital, 638, Ohira-ichibankochi, Yawatahama, Ehime 796-8502, Japan) ,  Ochi Fumihiro (Department of Pediatrics, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan) ,  Watanabe Asami (Department of Pediatrics, Yawatahama City General Hospital, 638, Ohira-ichibankochi, Yawatahama, Ehime 796-8502, Japan) ,  Watanabe Asami (Department of Pediatrics, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan) ,  Kawakami Sanae (Department of Pediatrics, Yawatahama City General Hospital, 638, Ohira-ichibankochi, Yawatahama, Ehime 796-8502, Japan) ,  Kuzume Kazuyo (Department of Pediatrics, Yawatahama City General Hospital, 638, Ohira-ichibankochi, Yawatahama, Ehime 796-8502, Japan) ,  Kuzume Kazuyo (Department of Community and Emergency Medicine, Ehime University School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan) ,  Watanabe Kenji (Department of Pediatrics, Kagoshima City Hospital, 37-1, Uearata-cho, Kagoshima 890-8760, Japan) ,  Sameshima Koji (Department of Pediatrics, Kagoshima City Hospital, 37-1, Uearata-cho, Kagoshima 890-8760, Japan) ,  Nakamagoe Kiyotaka (Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennoudai, Tsukuba, Ibaraki 305-8575, Japan) ,  Tamaoka Akira (Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennoudai, Tsukuba, Ibaraki 305-8575, Japan) ,  Asahina Naoko (Department of Pediatrics, Hokkaido University School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan) ,  Yokoshiki Saki (Hokkaido University Hospital Clinical Research and Medical Innovation Center, Research and Development Division, Kita 14, Nishi 5, Kita-ku, Sapporo 060-8648, Japan) ,  Miyakoshi Takashi (Hokkaido University Hospital Clinical Research and Medical Innovation Center, Research and Development Division, Kita 14, Nishi 5, Kita-ku, Sapporo 060-8648, Japan) ,  Ono Kota (Hokkaido University Hospital Clinical Research and Medical Innovation Center, Biostatistics Division, Kita 14, Nishi 5, Kita-ku, Sapporo 060-8648, Japan) ,  Oba Koji (Department of Biostatistics, School of Public Health, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Isoe Toshiyuki (Hokkaido University Hospital Clinical Research and Medical Innovation Center, Research and Development Division, Kita 14, Nishi 5, Kita-ku, Sapporo 060-8648, Japan) ,  Hayashi Hiroshi (Hokkaido University Hospital Clinical Research and Medical Innovation Center, Research and Development Division, Kita 14, Nishi 5, Kita-ku, Sapporo 060-8648, Japan) ,  Yamaguchi Seiji (Department of Pediatrics, Shimane University Faculty of Medicine, 89-1, En-ya-cho, Izumo, Shimane 693-8501, Japan) ,  Sato Norihiro (Hokkaido University Hospital Clinical Research and Medical Innovation Center, Kita 14, Nishi 5, Kita-ku, Sapporo 060-8648, Japan)
Material： Molecular Genetics and Metabolism Reports
Volume： 15  Page： 55-63  Publication year： 2018 
JST Material Number： W2993A  ISSN： 2214-4269  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Fatty acid oxidation disorders...

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Thesaurus term： serum ,  administration(biology) ,  seizure(disease) ,  mitochondria ,  *therapy ,  in vitro experiment ,  carnitine O-palmitoyltransferase ,  muscular disease ,  *patient ,  *clinical trial ,  *Japan ,  creatine kinase ,  aromatic carboxylic acid ,  aromatic chlorine compound ,  carboxamide ,  phenol ether
Semi thesaurus term： エンドポイント ,  *脂肪酸酸化 , 【Automatic Indexing@JST】

Author keywords (5)： Bezafibrate ,  Fatty acid oxidation disorders (FAODs) ,  Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency ,  Carnitine palmitoyltransferase-II (CPT-2) deficiency ,  Clinical trial

JST classification (3)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Metabolism in general  (EB05030X) ,  Gene expression  (EC02040Q)

Substance index (1)： Bezafibrate

Terms in the title (8)： 日本 ,  脂肪酸 ,  酸化障害 ,  患者 ,  ベザフィブラート ,  治療 ,  ラベル ,  臨床試験