Art

J-GLOBAL ID：201802217315677413   Reference number：18A1489247

Nr4a Receptors Regulate Development and Death of Labile Treg Precursors to Prevent Generation of Pathogenic Self-Reactive Cells

NR4A受容体は病原性自己反応性細胞の発生を防ぐために不安定なTreg前駆体の発生と死を調節する【JST・京大機械翻訳】

Author (8)： Sekiya Takashi (Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Sekiya Takashi (Section of Immune Response Modification, The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa, Chiba 272-8516, Japan) ,  Sekiya Takashi (Department of Immune Regulation, The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa, Chiba 272-8516, Japan) ,  Hibino Sana (Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Saeki Keita (Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Kanamori Mitsuhiro (Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Takaki Satoshi (Department of Immune Regulation, The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa, Chiba 272-8516, Japan) ,  Yoshimura Akihiko (Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan)
Material： Cell Reports
Volume： 24  Issue： 6  Page： 1627-1638.e6  Publication year： 2018 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Regulatory T (Treg) cells deve...

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Thesaurus term： *reactivity ,  thymocyte ,  cell death ,  autoimmunity ,  defence mechanism ,  *precursor(substance) ,  inflammatory cytokine ,  immunological tolerance ,  *reproductive cell ,  CD4 antigen ,  *pathogenicity ,  *regulatory T cell
Semi thesaurus term： FoxP3 ,  有害事象 ,  前駆細胞 , 【Automatic Indexing@JST】

Author keywords (6)： Treg ,  Nr4a ,  Foxp3 ,  negative selection ,  immune tolerance ,  inflammatory cytokine

JST classification (1)： Immunological reaction in general  (ED03010T)

Terms in the title (8)： 受容体 ,  病原性 ,  自己 ,  性細胞 ,  Treg ,  前駆体 ,  死 ,  調節