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J-GLOBAL ID：201802217333287926   Reference number：18A0490102

A phase II study of nab-paclitaxel in combination with ramucirumab in patients with previously treated advanced gastric cancer

以前に治療した進行胃癌患者のラムシルマブと併用したnab-パクリタキセルの第II相試験【Powered by NICT】

Author (13)： Bando Hideaki (Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan) ,  Shimodaira Hideki (Department of Clinical Oncology, Tohoku University Hospital, Sendai, Japan) ,  Fujitani Kazumasa (Department of Surgery, Osaka General Medical Center, Osaka, Japan) ,  Takashima Atsuo (Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan) ,  Yamaguchi Kensei (Department of Gastroenterological Chemotherapy, The Cancer Institute Hospital Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Nakayama Norisuke (Department of Gastroenterology, Kanagawa Cancer Center, Yokohama, Japan) ,  Takahashi Takehiro (Institute of Molecular Oncology, Showa University School of Medicine, Tokyo, Japan) ,  Oki Eiji (Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Azuma Mizutomo (Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Japan) ,  Nishina Tomohiro (Department of Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan) ,  Hironaka Shuichi (Clinical Trial Promotion Department, Chiba Cancer Center, Chiba, Japan) ,  Komatsu Yoshito (Division of Cancer Chemotherapy, Hokkaido University Hospital, Sapporo, Japan) ,  Shitara Kohei (Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan)
Material： European Journal of Cancer  (Eur J Cancer)
Volume： 91  Page： 86-91  Publication year： 2018 
JST Material Number： A0802C  ISSN： 0959-8049  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Nanoparticle albumin-bound (na...

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Thesaurus term： combination therapy ,  anemia ,  safety ,  toxicity ,  hypertension ,  albumin ,  *phase 2 study ,  anorexia ,  *patient ,  median value ,  alicyclic compound ,  fatty acid ,  aromatic carboxylic acid ,  oxygen heterocyclic compound ,  olefin compound ,  bridged compound ,  carboxylate(ester) ,  aminoalcohol ,  aminocarboxylic acid ,  secondary alcohol ,  hydroxy acid ,  hydroxy ketone ,  polyol
Semi thesaurus term： 有害事象 ,  エンドポイント ,  *ラムシルマブ ,  *進行胃癌 , 【Automatic Indexing@JST】

Author keywords (6)： Advanced gastric cancer ,  Nab-paclitaxel ,  Paclitaxel ,  Ramucirumab ,  Overall response rate ,  Second-line chemotherapy

JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (1)： Paclitaxel

Terms in the title (7)： 治療 ,  進行胃癌 ,  患者 ,  ラムシルマブ ,  併用 ,  nab-パクリタキセル ,  第II相試験