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J-GLOBAL ID：201802218016621985   Reference number：18A0363116

Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy

p210 BCR-ABLのプレクストリン相同ドメインはカルジオリピンと相互作用してそのミトコンドリア移行とその後のマイトファジーを制御する

Author (13)： Shimasaki Kentaro (Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan) ,  Watanabe-Takahashi Miho (Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan) ,  Umeda Masato (Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan) ,  Funamoto Satoru (Department of Neuropathology, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan) ,  Saito Yoshiro (Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan) ,  Noguchi Noriko (Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan) ,  Kumagai Keigo (Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases, Tokyo, Japan) ,  Hanada Kentaro (Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases, Tokyo, Japan) ,  Tsukahara Fujiko (Department of Pharmacology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Maru Yoshiro (Department of Pharmacology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Shibata Norihito (Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Tokyo, Japan) ,  Naito Mikihiko (Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Tokyo, Japan) ,  Nishikawa Kiyotaka (Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan)
Material： Genes to Cells  (Genes Cells)
Volume： 23  Issue： 1  Page： 22-34  Publication year： Jan. 2018 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *tertiary structure ,...
Semi thesaurus term： *Pleckstrin Homology Domains ,...

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Author keywords (6)： cardiolipin ,  mitochondria ,  mitophagy ,  p210 BCR-ABL ,  pleckstrin homology domain ,  reactive oxygen species

JST classification (4)： Cell components in general  (EF03010Z) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Substance index (1)： Carbonyl Cyanide m-Chlorophenyl Hydrazone

Terms in the title (7)： BCR-ABL ,  プレクストリン相同ドメイン ,  カルジオリピン ,  相互作用 ,  ミトコンドリア ,  移行 ,  マイトファジー