Art

J-GLOBAL ID：201802218172256353   Reference number：18A2155338

Pharmacodynamical effects of orally administered exenatide nanoparticles embedded in gastro-resistant microparticles

胃抵抗性微粒子に埋め込まれた経口投与されたExenatideナノ粒子の薬物動力学的効果【JST・京大機械翻訳】

Author (9)： Soudry-Kochavi Liat (The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem, Jerusalem 9112102, Israel) ,  Naraykin Natalya (The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem, Jerusalem 9112102, Israel) ,  Di Paola Rosanna (Pharmacology Department, University of Messina, Via San Filippo Bianchi 19, Messina 98123, Italy) ,  Gugliandolo Enrico (Pharmacology Department, University of Messina, Via San Filippo Bianchi 19, Messina 98123, Italy) ,  Peritore Alessio (Pharmacology Department, University of Messina, Via San Filippo Bianchi 19, Messina 98123, Italy) ,  Cuzzocrea Salvatore (Pharmacology Department, University of Messina, Via San Filippo Bianchi 19, Messina 98123, Italy) ,  Ziv Ehud (Diabetes Unit, Division of Internal Medicine, Hadassah Ein Kerem Hospital, Jerusalem 9112102, Israel) ,  Nassar Taher (The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem, Jerusalem 9112102, Israel) ,  Benita Simon (The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem, Jerusalem 9112102, Israel)
Material： European Journal of Pharmaceutics and Biopharmaceutics  (Eur J Pharm Biopharm)
Volume： 133  Page： 214-223  Publication year： 2018 
JST Material Number： B0129B  ISSN： 0939-6411  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： One of the major disadvantages...

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Thesaurus term： *oral administration ,  insulin ,  blood glucose ,  diabetes mellitus ,  *nano particle ,  effectiveness ,  mouse(animal) ,  drug delivery system ,  therapy ,  body weight
Semi thesaurus term： ob/obマウス ,  経口バイオアベイラビリティ ,  注射 ,  GLP-1アナログ製剤 ,  経口ドラッグデリバリー , 【Automatic Indexing@JST】

Author keywords (6)： Nanoparticles ,  Microparticles ,  Exenatide ,  Peptides ,  Diabetes ,  Oral

JST classification (1)： Basic biopharmacy  (GY01021U)

Terms in the title (6)： 胃 ,  抵抗性 ,  微粒子 ,  経口投与 ,  ナノ粒子 ,  薬物動力学