Art

J-GLOBAL ID：201802218908147907   Reference number：18A1006795

Relevance of FXR-p62/SQSTM1 pathway for survival and protection of mouse hepatocytes and liver, especially with steatosis

マウス肝細胞と肝臓の生存と保護のためのFXR-p62/SQSTM1経路の関連性,特に脂肪症について【JST・京大機械翻訳】

Author (3)： Haga Sanae (Department of Biological Response and Regulation, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan) ,  Yimin (Department of Advanced Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Ozaki Michitaka (Department of Biological Response and Regulation, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan)
Material： BMC Gastroenterology (Web)
Volume： 17  Issue： 1  Page： 9  Publication year： 2017 
JST Material Number： U7426A  ISSN： 1471-230X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Background Liver injury and re...

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Thesaurus term： antioxidation ,  gene ,  up-regulation ,  hepatic dysfunction ,  *hepatocyte ,  hepatectomy ,  Fas antigen ,  oxidative stress ,  protective action ,  fatty liver ,  phosphorylation ,  serum concentration ,  siRNA
Semi thesaurus term： *p62 ,  細胞生存 , 【Automatic Indexing@JST】

Author keywords (7)： FXR ,  p62/SQSTM1 ,  Nrf2 ,  SHP ,  Oxidative stress ,  Liver injury ,  Steatosis

JST classification (1)： Basic medicine on digestive system  (GH01020E)

Reference (33)：

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• Hepatology; Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-A(y) mice; T Aoyama, K Ikejima, K Kon, K Okumura, K Arai, S Watanabe; 49; 2009; 1636-44; 10.1002/hep.22828; CR4;
• Ann Surg; Single administration of thrombopoietin prevents progression of liver fibrosis and promotes liver regeneration after partial hepatectomy in cirrhotic rats; S Murata, I Hashimoto, Y Nakano, A Myronovych, M Watanabe, N Ohkohchi; 248; 2008; 821-8; 10.1097/SLA.0b013e31818584c7; CR5;

Terms in the title (10)： マウス ,  肝細胞 ,  肝臓 ,  生存 ,  FXR ,  p62 ,  SQSTM1 ,  経路 ,  関連性 ,  脂肪症