Art

J-GLOBAL ID：201802219126927259   Reference number：18A1188556

Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations

カルレチクリン突然変異を持つヒト誘導多能性幹細胞由来造血前駆細胞における歪んだmegakar【JST・京大機械翻訳】

Author (19)： Takei Hiraku (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Edahiro Yoko (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Mano Shuichi (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Mano Shuichi (Department of Life Science and Medical Bioscience, Waseda University Graduate School, Tokyo, Japan) ,  Masubuchi Nami (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Masubuchi Nami (Research Institute for Disease of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Mizukami Yoshihisa (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Mizukami Yoshihisa (Centre for Genomic and Regenerative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Imai Misa (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Morishita Soji (Department of Transfusion Medicine and Stem Cell Regulation, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Misawa Kyohei (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Ochiai Tomonori (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Tsuneda Satoshi (Department of Life Science and Medical Bioscience, Waseda University Graduate School, Tokyo, Japan) ,  Endo Hiroshi (Department of Clinical Application, CiRA, Kyoto University, Kyoto, Japan) ,  Nakamura Sou (Department of Clinical Application, CiRA, Kyoto University, Kyoto, Japan) ,  Eto Koji (Department of Clinical Application, CiRA, Kyoto University, Kyoto, Japan) ,  Ohsaka Akimichi (Department of Transfusion Medicine and Stem Cell Regulation, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Araki Marito (Department of Transfusion Medicine and Stem Cell Regulation, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Komatsu Norio (Department of Haematology, Juntendo University Graduate School of Medicine, Tokyo, Japan)
Material： British Journal of Haematology  (Br J Haematol)
Volume： 181  Issue： 6  Page： 791-802  Publication year： 2018 
JST Material Number： C0969B  ISSN： 0007-1048  CODEN： BJHEAL  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Somatic mutations in the calre...

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Thesaurus term： cell differentiation ,  patient ,  therapy ,  in vitro experiment ,  *mutation ,  gene ,  *variation(biology) ,  bone marrow ,  *human(primates) ,  megakaryocyte
Semi thesaurus term： 大核 ,  *前駆細胞 ,  造血細胞 ,  *造血前駆細胞 ,  *カルレチクリン , 【Automatic Indexing@JST】

Author keywords (5)： myeloproliferative neoplasm ,  calreticulin ,  induced pluripotent stem cells ,  megakaryopoiesis ,  anagrelide

JST classification (4)： Cell and tissue culture methods  (EA03040R) ,  Basic hematology  (GK01020N) ,  Hematopoietic system  (EJ07020Y) ,  Cell physiology in general  (EF02010S)

Terms in the title (6)： カルレチクリン ,  突然変異 ,  ヒト ,  誘導 ,  多能性幹細胞 ,  造血前駆細胞