Art

J-GLOBAL ID：201802219348620017   Reference number：18A0939806

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

絶食はホメオスタシスと加齢中の腸幹細胞機能を増強するために脂肪酸酸化を活性化する【JST・京大機械翻訳】

Author (43)： Mihaylova Maria M. (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Mihaylova Maria M. (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Mihaylova Maria M. (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Mihaylova Maria M. (Howard Hughes Medical Institute, Chevy Chase, MD, USA) ,  Cheng Chia-Wei (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Cheng Chia-Wei (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Cao Amanda Q. (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Cao Amanda Q. (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Cao Amanda Q. (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Cao Amanda Q. (Howard Hughes Medical Institute, Chevy Chase, MD, USA) ,  Tripathi Surya (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Mana Miyeko D. (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Mana Miyeko D. (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Bauer-Rowe Khristian E. (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Bauer-Rowe Khristian E. (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Abu-Remaileh Monther (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Abu-Remaileh Monther (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Abu-Remaileh Monther (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Abu-Remaileh Monther (Howard Hughes Medical Institute, Chevy Chase, MD, USA) ,  Clavain Laura (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Clavain Laura (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Clavain Laura (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Clavain Laura (Howard Hughes Medical Institute, Chevy Chase, MD, USA) ,  Erdemir Aysegul (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Erdemir Aysegul (Faculty of Arts & Sciences, Department of Molecular Biology and Genetics, Yildiz Technical University, 34210 Istanbul, Turkey) ,  Lewis Caroline A. (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Freinkman Elizaveta (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Dickey Audrey S. (Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA) ,  La Spada Albert R. (Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA) ,  Huang Yanmei (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Bell George W. (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Deshpande Vikram (Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA) ,  Carmeliet Peter (Laboratory of Angiogenesis and Neurovascular Link, Department of Oncology, KU Leuven, 3000 Leuven, Belgium) ,  Carmeliet Peter (Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB, 3000 Leuven, Belgium) ,  Katajisto Pekka (Institute of Biotechnology, HiLIFE, University of Helsinki, P.O. Box 56, Helsinki, Finland) ,  Katajisto Pekka (Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Stockholm, Sweden) ,  Sabatini David M. (Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA) ,  Sabatini David M. (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Sabatini David M. (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Sabatini David M. (Howard Hughes Medical Institute, Chevy Chase, MD, USA) ,  Yilmaz OEmer H. (The David H. Koch Institute for Integrative Cancer Research at MIT, Department of Biology, MIT, Cambridge, MA 02139, USA) ,  Yilmaz OEmer H. (Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA) ,  Yilmaz OEmer H. (Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA)
Material： Cell Stem Cell
Volume： 22  Issue： 5  Page： 769-778.e4  Publication year： 2018 
JST Material Number： W3106A  ISSN： 1934-5909  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Diet has a profound effect on ...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A0939806&from=J-GLOBAL&jstjournalNo=W3106A") }}

Thesaurus term： rate-limiting ,  mitochondria ,  pharmacological action ,  *fasting ,  adult(development) ,  *stem cell ,  heredity ,  *homeostasis ,  enzyme ,  metabolism
Semi thesaurus term： 前駆細胞 ,  健康 ,  組織再生 ,  *脂肪酸酸化 ,  *腸幹細胞 , 【Automatic Indexing@JST】

Author keywords (8)： stem cells ,  intestinal stem cells ,  fasting ,  aging ,  metabolism ,  intestine ,  fatty acid oxidation ,  mitochondrial metabolism

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (7)： 絶食 ,  ホメオスタシス ,  加齢 ,  腸幹細胞 ,  増強 ,  脂肪酸酸化 ,  活性化