Art

J-GLOBAL ID：201802220626445188   Reference number：18A1785518

Effects of Supplementary Seleno-L-methionine on Atopic Dermatitis-Like Skin Lesions in Mice

マウスにおけるアトピー性皮膚炎様皮膚病変に対するセレノ-L-メチオニン補充の効果

Author (7)： Arakawa Tomohiro (Department of Public Health & Preventive Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Sugiyama Takahiro (Department of Public Health & Preventive Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Matsuura Haruka (Department of Public Health & Preventive Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Okuno Tomofumi (Department of Public Health & Preventive Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Ogino Hirofumi (Department of Public Health & Preventive Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Sakazaki Fumitoshi (Laboratory of Toxicology, Faculty of Pharmacy, Osaka Ohtani University) ,  Ueno Hitoshi (Department of Public Health & Preventive Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University)
Material： Biological and Pharmaceutical Bulletin (Web)
Volume： 41  Issue： 9  Page： 1456-1462(J-STAGE)  Publication year： 2018 
JST Material Number： U1402A  ISSN： 1347-5215  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： mRNA expression ,...

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Author keywords (10)： atopic dermatitis ,  seleno-L-methionine ,  immunoglobulin E ,  interleukin 4 ,  246-trinitrochlorobenzene ,  atopic dermatitis ,  seleno-L-methionine ,  immunoglobulin E ,  interleukin 4 ,  246-trinitrochlorobenzene

JST classification (4)： Basic dermatology  (GF01020Y) ,  Integument in general  (EJ11010C) ,  Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D)

Substance index (1)： Selenomethionine

Reference (43)：

• 1) Weidinger S, Novak N. Atopic dermatitis. Lancet, 387, 1109-1122 (2016).
• 2) Simpson EL, Bieber T, Eckert L, Wu R, Ardeleanu M, Graham NMH, Pirozzi G, Mastey V. Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults. J. Am. Dermatology., 74, 491-498 (2016).
• 3) Bos JD, Kapsenberg ML, Smitt JH. Pathogenesis of atopic eczema. Lancet, 343, 1338-1341 (1994).
• 4) Muller KM, Jaunin F, Masouye I, Saurat JH, Hauser C. Th2 cells mediate IL-4-dependent local tissue inflammation. J. Immunol., 150, 5576-5584 (1993).
• 5) Leung DY. Atopic dermatitis: new insights and opportunities for therapeutic intervention. J. Allergy Clin. Immunol., 105, 860-876 (2000).

Terms in the title (5)： マウス ,  アトピー性皮膚炎 ,  皮膚病変 ,  セレノ-L-メチオニン ,  補充