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J-GLOBAL ID：201802220748106466   Reference number：18A0930675

A phase I/II exploratory clinical trial for intracordal injection of recombinant hepatocyte growth factor for vocal fold scar and sulcus

声帯瘢痕および溝に対する組換え肝細胞増殖因子の内注入のための第I/II相試験臨床試験【JST・京大機械翻訳】

Author (15)： Hirano Shigeru (Department of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Kawamoto Atsuhiko (Unit of Regenerative Medicine, Institute of Biomedical Research and Innovation/Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, Japan) ,  Tateya Ichiro (Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Kyoto, Japan) ,  Mizuta Masanobu (Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Kyoto, Japan) ,  Kishimoto Yo (Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Kyoto, Japan) ,  Hiwatashi Nao (Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Kyoto, Japan) ,  Kawai Yoshitaka (Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Kyoto, Japan) ,  Tsuji Takuya (Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Kyoto, Japan) ,  Suzuki Ryo (Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Kyoto, Japan) ,  Kaneko Mami (Department of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Naito Yasushi (Department of Otolaryngology, Kobe City Medical Center General Hospital, Kobe, Japan) ,  Kagimura Tatsuo (Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, Japan) ,  Nakamura Tatsuo (Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan) ,  Kanemaru Shin-ichi (Department of Otolaryngology, Kitano Hospital, Osaka, Japan) ,  Kanemaru Shin-ichi (Institute of Biomedical Research and Innovation, Kobe, Japan)
Material： Journal of Tissue Engineering and Regenerative Medicine
Volume： 12  Issue： 4  Page： 1031-1038  Publication year： 2018 
JST Material Number： W2668A  ISSN： 1932-6254  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Vocal fold scar and sulcus are...

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Thesaurus term： administration(biology) ,  vocalization ,  protocol ,  human(primates) ,  therapy ,  *HGF ,  safety ,  asthma ,  patient ,  *cicatrix ,  *vocal cord ,  *clinical trial
Semi thesaurus term： 有害事象 ,  音声障害 ,  エンドポイント , 【Automatic Indexing@JST】

Author keywords (6)： clinical trial ,  first in human ,  hepatocyte growth factor ,  regeneration ,  sulcus vocalis ,  vocal fold scar

JST classification (1)： Bioactive peptides  (EB08100U)

Terms in the title (7)： 声帯 ,  瘢痕 ,  組換え ,  肝細胞増殖因子 ,  注入 ,  試験 ,  臨床試験