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J-GLOBAL ID：201802222680384211   Reference number：18A1913651

Characteristics of Bone Strength and Metabolism in Type 2 Diabetic Model Nagoya Shibata Yasuda Mice

2型糖尿病モデルNagoya Shibata Yasudaマウスにおける骨強度と骨代謝の特性

Author (5)： Tanaka Hiroaki (Graduate School of Health Science, Suzuka University of Medical Science) ,  Miura Toshihiro (Graduate School of Health Science, Suzuka University of Medical Science) ,  Yamashita Takenori (Department of Radiological Technology, Faculty of Health Science, Suzuka University of Medical Science) ,  Yoneda Misao (Department of Clinical Nutrition, Faculty of Health Science, Suzuka University of Medical Science) ,  Takagi Satoshi (Department of Physical Therapy, Faculty of Health and Medical Sciences, Tokoha University)
Material： Biological and Pharmaceutical Bulletin (Web)
Volume： 41  Issue： 10  Page： 1567-1573(J-STAGE)  Publication year： 2018 
JST Material Number： U1402A  ISSN： 1347-5215  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...

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Author keywords (12)： Nagoya Shibata Yasuda mouse ,  bone strength ,  bone metabolism ,  type 2 diabetes mellitus ,  bone mass ,  bone microstructure ,  Nagoya Shibata Yasuda mouse ,  bone strength ,  bone metabolism ,  type 2 diabetes mellitus ,  bone mass ,  bone microstructure

JST classification (4)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Skeletal system  (EJ10030R) ,  Basic medicine on musculoskeletal system  (GG01020B) ,  Metabolism and nutrition of sugar(=glucide)  (EJ02035H)

Reference (44)：

• 1) Janghorbani M, Van Dam RM, Willett WC, Hu FB. Systematic review of type 1 and type 2 diabetes mellitus and risk of fracture. Am. J. Epidemiol., 166, 495-505 (2007).
• 2) Vestergaard P. Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes-a meta-analysis. Osteoporos. Int., 18, 427-444 (2007).
• 3) Yang J, Zhang X, Wang W, Liu J. Insulin stimulates osteoblast proliferation and differentiation through ERK and PI3K in MG-63 cells. Cell Biochem. Funct., 28, 334-341 (2010).
• 4) Valerio G, del Puente A, Esposito-del Puente A, Buono P, Mozzillo E, Franzese A. The lumbar bone mineral density is affected by long-term poor metabolic control in adolescents with type 1 diabetes mellitus. Horm. Res., 58, 266-272 (2002).
• 5) Yamamoto M, Yamaguchi T, Yamauchi M, Kaji H, Sugimoto T. Diabetic patients have an increased risk of vertebral fractures independent of BMD or diabetic complications. J. Bone Miner. Res., 24, 702-709 (2009).

Terms in the title (5)： 2型糖尿病 ,  モデル ,  マウス ,  骨強度 ,  骨代謝