Art

J-GLOBAL ID：201802223182486991   Reference number：18A0986489

A novel high-sensitivity assay to detect a small fraction of mutant IDH1 using droplet digital PCR

ドロップレットデジタルPCRを用いて微量の変異IDH1を検出する新規の高感度アッセイ

Author (17)： HIRANO Masaki (Nagoya Univ., Nagoya, JPN) ,  OHKA Fumiharu (Nagoya Univ., Nagoya, JPN) ,  MAEDA Sachi (Nagoya Univ., Nagoya, JPN) ,  CHALISE Lushun (Nagoya Univ., Nagoya, JPN) ,  YAMAMICHI Akane (Nagoya Univ., Nagoya, JPN) ,  YAMAMICHI Akane (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  YAMAMICHI Akane (Mie Univ., Tsu, JPN) ,  AOKI Kosuke (Nagoya Univ., Nagoya, JPN) ,  KATO Akira (Nagoya Univ., Nagoya, JPN) ,  TANAHASHI Kuniaki (Nagoya Univ., Nagoya, JPN) ,  MOTOMURA Kazuya (Nagoya Univ., Nagoya, JPN) ,  NISHIMURA Yusuke (Nagoya Univ., Nagoya, JPN) ,  HARA Masahito (Nagoya Univ., Nagoya, JPN) ,  SHINJO Keiko (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  KONDO Yutaka (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  WAKABAYASHI Toshihiko (Nagoya Univ., Nagoya, JPN) ,  NATSUME Atsushi (Nagoya Univ., Nagoya, JPN)
Material： Brain Tumor Pathology  (Brain Tumor Pathol)
Volume： 35  Issue： 2  Page： 97-105  Publication year： 2018 
JST Material Number： L2617A  ISSN： 1433-7398  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *polymerase chain reaction ,...
Semi thesaurus term： genetic variation ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A0986489&from=J-GLOBAL&jstjournalNo=L2617A") }}

JST classification (1)： Neurologic diagnosis  (GN02000H)

Reference (28)：

• Suzuki H, Aoki K, Chiba K, Sato Y, Shiozawa Y, Shiraishi Y, Shimamura T, Niida A, Motomura K, Ohka F et al (2015) Mutational landscape and clonal architecture in grade II and III gliomas. Nat Genet 47:458-468
• Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O et al (2015) Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med 372:2481-2498
• Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131:803-820
• Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, Inserra E, Diederichs S, Iafrate AJ, Bell DW et al (2008) Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med 359:366-377
• Rothe F, Laes JF, Lambrechts D, Smeets D, Vincent D, Maetens M, Fumagalli D, Michiels S, Drisis S, Moerman C et al (2014) Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer. Ann Oncol 25:1959-1965

Terms in the title (6)： ドロップレット ,  デジタルPCR ,  変異 ,  IDH1 ,  高感度 ,  アッセイ