Art

J-GLOBAL ID：201802223301240457   Reference number：18A1014088

A High-Fat and High-Cholesterol Diet Induces Cardiac Fibrosis, Vascular Endothelial, and Left Ventricular Diastolic Dysfunction in SHRSP5/Dmcr Rats

SHRSP5/Dmcrラットにおいて高脂肪および高コレステロール食は,心臓線維症,血管内皮および左心室拡張機能障害を誘発する

Author (14)： Watanabe Shogo (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kumazaki Shota (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kusunoki Katsuhiro (Department of Medical Technology, Faculty of Health Sciences, Okayama University) ,  Inoue Terumi (Department of Medical Technology, Faculty of Health Sciences, Okayama University) ,  Maeda Yui (Department of Medical Technology, Faculty of Health Sciences, Okayama University) ,  Usui Shinichi (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Shinohata Ryoko (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Ohtsuki Takashi (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Hirohata Satoshi (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kusachi Shozo (Department of Medical Technology, Graduate School of Health Sciences, Okayama University) ,  Kitamori Kazuya (College of Human Life and Environment, Kinjo Gakuin University) ,  Mori Mari (Institute for World Health Development, Mukogawa Women’s University) ,  Yamori Yukio (Institute for World Health Development, Mukogawa Women’s University) ,  Oka Hisao (Department of Medical Technology, Graduate School of Health Sciences, Okayama University)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 25  Issue： 5  Page： 439-453(J-STAGE)  Publication year： 2018 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： experimental disease ,...
Semi thesaurus term： *Diastolic dysfunction ,...

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Author keywords (6)： Atherosclerosis ,  Non-alcoholic steatohepatitis ,  SHRSP5/Dmcr ,  Endothelial function ,  High-fat ,  High-cholesterol diets

JST classification (3)： Basic medicine on cardiovascular system  (GJ01020K) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Circulation system in general  (EJ04010S)

Reference (53)：

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• 3) Gordts PL, Bartelt A, Nilsson SK, Annaert W, Christoffersen C, Nielsen LB, Heeren J, Roebroek AJ: Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice. PLoS One, 2012; 7: e38330
• 4) Kitamori K, Naito H, Tamada H, Kobayashi M, Miyazawa D, Yasui Y, Sonoda K, Tsuchikura S, Yasui N, Ikeda K, Moriya T, Yamori Y, Nakajima T: Development of novel rat model for high-fat and high-cholesterol dietinduced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr. Environ Health Prev Med, 2012; 17: 173-182
• 5) Yamori Y, Kitamura Y, Nara Y, Iritani N: Mechanism of hypercholesterolemia in arteriolipidosis-prone rats (ALR). Jpn Circ J, 1981; 45: 1068-1073

Terms in the title (8)： ラット ,  脂肪 ,  高コレステロール食 ,  心臓線維症 ,  血管内皮 ,  左心室拡張 ,  機能障害 ,  誘発