Art

J-GLOBAL ID：201802223439470010   Reference number：18A1599965

Differential effects of depot formulations of GnRH agonist leuprorelin and antagonist degarelix on the seminiferous epithelium of the rat testis

ラット精巣精上皮に対するGnRH作動薬ロイプロレリンと拮抗薬デガレリックスデポ製剤の差次的影響

Author (5)： HORI Jun-ichi (Department of Microscopic Anatomy and Cell Biology, Asahikawa Medical University) ,  HORI Jun-ichi (Department of Renal and Urologic Surgery, Asahikawa Medical University) ,  KOGA Daisuke (Department of Microscopic Anatomy and Cell Biology, Asahikawa Medical University) ,  KAKIZAKI Hidehiro (Department of Renal and Urologic Surgery, Asahikawa Medical University) ,  WATANABE Tsuyoshi (Department of Microscopic Anatomy and Cell Biology, Asahikawa Medical University)
Material： Biomedical Research (Web)
Volume： 39  Issue： 4  Page： 197-214(J-STAGE)  Publication year： 2018 
JST Material Number： U1102A  ISSN： 1880-313X  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *prostatic tumor ,...
Semi thesaurus term： Seminiferous Epithelium ,...

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JST classification (3)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Other hormones of verterbrates  (EB08070K) ,  Basic medicine on urogenital system  (GM01020T)

Substance index (2)： Leuprolide ,  Degarelix

Reference (65)：

• 1 Barbieri RL (1992) Clinical applications of GnRH and its analogues. Trends Endocrinol Metab 3, 30-34.
• 2 Bartles JR, Wierda A and Zheng L (1996) Identification and characterization of espin, an actin-binding protein localized to the F-actin-rich junctional plaques of Sertoli cell ectoplasmic specializations. J Cell Sci 109, 1229-1239.
• 3 Bartlett JM, Weinbauer GF and Nieschlag E (1989) Differential effects of FSH and testosterone on the maintenance of spermatogenesis in the adult hypophysectomized rat. J Endocrinol 121, 49-58.
• 4 Bhasin S, Fielder T, Peacock N, Sod-Moriah UA and Swerdloff RS (1988) Dissociating antifertility effects of GnRH-antagonist from its adverse effects on mating behavior in male rats. Am J Physiol 254, E84-91.
• 5 Bliss SP, Navratil AM, Xie J and Roberson MS (2010) GnRH signaling, the gonadotrope and endocrine control of fertility. Front Neuroendocrinol 31, 322-340.

Terms in the title (8)： ラット ,  精巣 ,  精上皮 ,  GnRH作動薬 ,  ロイプロレリン ,  拮抗薬 ,  デガレリックス ,  デポ製剤