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J-GLOBAL ID：201802224310258493   Reference number：18A0396975

Pharmacologic inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia

Notchシグナル伝達の薬理学的阻害は食品抗原誘発粘膜肥満細胞の過形成を抑制する【Powered by NICT】

Author (13)： Honjo Asuka (Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Nakano Nobuhiro (Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Yamazaki Susumu (Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Hara Mutsuko (Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Uchida Koichiro (Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Kitaura Jiro (Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Nishiyama Chiharu (Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Nishiyama Chiharu (Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Tokyo, Japan) ,  Yagita Hideo (Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan) ,  Ohtsuka Yoshikazu (Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Ogawa Hideoki (Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Okumura Ko (Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan) ,  Shimizu Toshiaki (Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan)
Material： Journal of Allergy and Clinical Immunology  (J Allergy Clin Immunol)
Volume： 139  Issue： 3  Page： 987-996.e10  Publication year： 2017 
JST Material Number： A0182B  ISSN： 0091-6749  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Mucosal mast cells (MMCs) play...

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Thesaurus term： intestinal mucosa ,  gene ,  food allergy ,  up-regulation ,  bone marrow ,  *food ,  differentiation(biology) ,  *Notch receptor ,  *antigen ,  small intestine ,  *mastocyte ,  allergic reaction ,  immunoglobulin E
Semi thesaurus term： マウスモデル ,  *Notchシグナリング , 【Automatic Indexing@JST】

Author keywords (4)： Notch signaling ,  mucosal mast cells ,  food allergy ,  mast cell hyperplasia

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (9)： Notchシグナル ,  薬理学 ,  阻害 ,  食品 ,  抗原 ,  誘発 ,  粘膜 ,  肥満細胞 ,  過形成