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J-GLOBAL ID：201802224416197671   Reference number：18A0465265

Lansoprazole prevents the progression of liver fibrosis in non-alcoholic steatohepatitis model rats

ランソプラゾールは非アルコール性脂肪性肝炎モデルラットにおける肝線維症の進行を予防する【Powered by NICT】

Author (11)： Nishi Toshio (Department of Anatomy and Cell Biology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Yamamoto Yuta (Department of Anatomy and Cell Biology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Yamagishi Naoko (Department of Anatomy and Cell Biology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Iguchi Mikitaka (2nd Department of Internal Medicine, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Tamai Hideyuki (2nd Department of Internal Medicine, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Ito Takao (Department of Anatomy and Cell Biology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Tsuruo Yoshihiro (Department of Anatomy and Cell Biology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Tsuruo Yoshihiro (Department of Anatomy and Cell Biology, Tokushima University Graduate School of Medical Science, Tokushima, Japan) ,  Ichinose Masao (2nd Department of Internal Medicine, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Kitano Masayuki (2nd Department of Internal Medicine, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan) ,  Ueyama Takashi (Department of Anatomy and Cell Biology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan)
Material： Journal of Pharmacy and Pharmacology  (J Pharm Pharmacol)
Volume： 70  Issue： 3  Page： 383-392  Publication year： 2018 
JST Material Number： C0332A  ISSN： 0022-3573  CODEN： JPPMAB  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： OBJECTIVES: We previously demo...

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Thesaurus term： interleukin 6 ,  aspartate aminotransferase ,  gene ,  *hepatic fibrosis ,  repeated administration ,  active oxygen ,  Serum ,  amyloid beta-protein ,  protein expression ,  Heme Oxygenase-1 ,  hepatoprotective effect ,  Models, Animal ,  Amyloid ,  glycoprotein ,  animal protein ,  ether ,  sulfoxide ,  nitrogen heterocyclic compound ,  organofluorine compound ,  polynuclear aromatic compound
Semi thesaurus term： 肝線維化 ,  *非アルコール性脂肪性肝炎 , 【Automatic Indexing@JST】

Author keywords (5)： IL-6 ,  non-alcoholic steatohepatitis ,  Nrf2 ,  pump inhibitor drug ,  TGF-beta

JST classification (1)： Basic biopharmacy  (GY01021U)

Substance index (1)： Lansoprazole

Terms in the title (5)： ランソプラゾール ,  非アルコール性脂肪性肝炎 ,  モデルラット ,  肝線維症 ,  予防