Art

J-GLOBAL ID：201802224557974412   Reference number：18A0947124

Detection of Acetaldehyde in the Esophageal Tissue among Healthy Male Subjects after Ethanol Drinking and Subsequent L-Cysteine Intake

エタノール飲酒およびその後のL-システイン摂取後の健常男性被験者の食道組織におけるアセトアルデヒドの検出

Author (11)： Okata Hideki (Division of Gastroenterology, Tohoku University Graduate School of Medicine) ,  Hatta Waku (Division of Gastroenterology, Tohoku University Graduate School of Medicine) ,  Iijima Katsunori (Department of Gastroenterology and Neurology, Akita University Graduate School of Medicine) ,  Asanuma Kiyotaka (Division of Gastroenterology, Tohoku University Graduate School of Medicine) ,  Tsuruya Atsuki (Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University) ,  Asano Naoki (Division of Gastroenterology, Tohoku University Graduate School of Medicine) ,  Koike Tomoyuki (Division of Gastroenterology, Tohoku University Graduate School of Medicine) ,  Hamada Shin (Division of Gastroenterology, Tohoku University Graduate School of Medicine) ,  Nakayama Toru (Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University) ,  Masamune Atsushi (Division of Gastroenterology, Tohoku University Graduate School of Medicine) ,  Shimosegawa Tooru (Division of Gastroenterology, Tohoku University Graduate School of Medicine)
Material： Tohoku Journal of Experimental Medicine  (Tohoku J Exp Med)
Volume： 244  Issue： 4  Page： 317-325(J-STAGE)  Publication year： 2018 
JST Material Number： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： single blind test ,...

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Author keywords (5)： acetaldehyde ,  acetaldehyde dehydrogenase ,  esophageal tissue ,  L-cysteine ,  placebo.

JST classification (1)： Influence on humans  (EE05050C)

Substance index (3)： Cysteine ,  Acetaldehyde ,  Ethanol

Reference (31)：

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• Cui, R., Kamatani, Y., Takahashi, A., Usami, M., Hosono, N., Kawaguchi, T., Tsunoda, T., Kamatani, N., Kubo, M., Nakamura, Y. & Matsuda, K. (2009) Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. <i>Gastroenterology</i>, 137, 1768-1775.
• Eriksson, C.J., Hillbom, M.E. & Sovijarvi, A. (1979) Difficulties in measuring human acetaldehyde levels. <i>Drug Alcohol Depend.</i>, 4, 148.

Terms in the title (9)： エタノール ,  飲酒 ,  L-システイン ,  摂取 ,  男性 ,  被験者 ,  食道 ,  組織 ,  アセトアルデヒド