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J-GLOBAL ID：201802226415279403   Reference number：18A0471857

A Novel Construction of Lentiviral Vectors for Eliminating Tumorigenic Cells from Pluripotent Stem Cells

多能性幹細胞からの除去腫瘍細胞のためのレンチウイルスベクターの新しい構築【Powered by NICT】

Author (12)： Ide Kanako (Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Mitsui Kaoru (Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Mitsui Kaoru (Center for Innovative Therapy Research and Application, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Irie Rie (Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Irie Rie (Center for Innovative Therapy Research and Application, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Matsushita Yohei (Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Ijichi Nobuhiro (Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Ijichi Nobuhiro (Center for Innovative Therapy Research and Application, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Toyodome Soichiro (Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Kosai Ken-ichiro (Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Kosai Ken-ichiro (Center for Innovative Therapy Research and Application, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Kosai Ken-ichiro (Center for Clinical and Translational Research, Kagoshima University Hospital, Kagoshima, Japan)
Material： Stem Cells  (Stem Cells (Durham))
Volume： 36  Issue： 2  Page： 230-239  Publication year： 2018 
JST Material Number： A0655C  ISSN： 1066-5099  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The risk of tumor formation po...

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Thesaurus term： plasmid ,  regenerative medicine ,  Teratoma ,  *tumor cell ,  promoter (genetics) ,  Thymidine Kinase ,  *tumor ,  cytotoxicity ,  transduction ,  *pluripotent stem cell ,  human ,  tumorigenesis ,  suicide gene ,  *Lentiviral vector ,  amine ,  ether ,  lactam ,  enzyme inhibitor ,  diol

Author keywords (8)： Lentiviral vector ,  Survivin ,  Suicide gene ,  Herpes simplex virus thymidine kinase ,  Stem cell ,  Tumorigenicity ,  Regenerative medicine ,  Gene therapy

JST classification (1)： Hematopoietic system  (EJ07020Y)

Substance index (1)： Ganciclovir

Terms in the title (4)： 多能性幹細胞 ,  腫瘍細胞 ,  レンチウイルスベクター ,  構築