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J-GLOBAL ID：201802226835059570   Reference number：18A0404095

Curcumin reduces the risk of chronic kidney damage in mice with nonalcoholic steatohepatitis by modulating endoplasmic reticulum stress and MAPK signaling

クルクミンは小胞体ストレスとMAPKシグナル伝達による非アルコール性脂肪性肝炎を有するマウスにおける慢性腎障害のリスクを減少させる【Powered by NICT】

Author (14)： Afrin Mst. Rejina (Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Arumugam Somasundaram (Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Arumugam Somasundaram (Department of Hematology, Endocrinology and Metabolism, Niigata University Graduate School of Medical and Dental Sciences, Niigata City 951-8510, Japan) ,  Rahman Md. Azizur (Department of Immunology and Medical Zoology, Faculty of Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata City 951-8510, Japan) ,  Karuppagounder Vengadeshprabhu (Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Harima Meilei (Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Suzuki Hiroshi (Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Suzuki Hiroshi (Department of Hematology, Endocrinology and Metabolism, Niigata University Graduate School of Medical and Dental Sciences, Niigata City 951-8510, Japan) ,  Miyashita Shizuka (Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Suzuki Kenji (Department of Clinical Engineering and Medical Technology, Niigata University of Health and Welfare, Niigata City 950-3198, Japan) ,  Ueno Kazuyuki (Department of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Yoneyama Hiroyuki (Stelic Institute & Co., Inc., Minato City, Tokyo 106-0044, Japan) ,  Watanabe Kenichi (Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan) ,  Watanabe Kenichi (Department of Hematology, Endocrinology and Metabolism, Niigata University Graduate School of Medical and Dental Sciences, Niigata City 951-8510, Japan)
Material： International Immunopharmacology  (Int Immunopharmacol)
Volume： 49  Page： 161-167  Publication year： 2017 
JST Material Number： T0026B  ISSN： 1567-5769  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Developing confirmation recomm...

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Thesaurus term： interleukin 1 ,  caspase ,  Apoptosis ,  inflammatory cytokine ,  Serum ,  MAP kinase ,  neonate ,  *Proteins ,  TNF alpha ,  high fat diet ,  oxidative stress ,  Caspase 3 ,  protein expression ,  diene ,  phenolic compound ,  phenol ether ,  enone ,  diketone

Author keywords (5)： Chronic kidney damage ,  ER stress ,  MAPK ,  Non-alcoholic fatty liver disease ,  Oxidative stress

JST classification (2)： Cytokines  (EB08090G) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (1)： Curcumin

Terms in the title (7)： クルクミン ,  小胞体ストレス ,  MAPKシグナル伝達 ,  非アルコール性脂肪性肝炎 ,  マウス ,  慢性腎障害 ,  リスク