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J-GLOBAL ID：201802227013203379   Reference number：18A0506526

Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4

自己分解を介して放出される肺炎球菌DNA結合蛋白質はToll様受容体4を介して炎症誘発性サイトカインの産生を誘導する【Powered by NICT】

Author (26)： Nagai Kosuke (Division of Microbiology and Infection Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Nagai Kosuke (Temporomandibular Joint Clinic, Niigata University Medical and Dental Hospital, Niigata, Japan) ,  Domon Hisanori (Division of Microbiology and Infection Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Domon Hisanori (Research Centre for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Maekawa Tomoki (Division of Microbiology and Infection Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Maekawa Tomoki (Research Centre for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Maekawa Tomoki (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Oda Masataka (Department of Microbiology and Infection Control Science, Kyoto Pharmaceutical University, Kyoto, Japan) ,  Hiyoshi Takumi (Division of Microbiology and Infection Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Hiyoshi Takumi (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tamura Hikaru (Division of Microbiology and Infection Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tamura Hikaru (Research Centre for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tamura Hikaru (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Yonezawa Daisuke (Division of Microbiology and Infection Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Yonezawa Daisuke (Research Centre for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Yonezawa Daisuke (Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Arai Yoshiaki (Temporomandibular Joint Clinic, Niigata University Medical and Dental Hospital, Niigata, Japan) ,  Yokoji Mai (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tabeta Koichi (Research Centre for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tabeta Koichi (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Habuka Rie (Department of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Saitoh Akihiko (Department of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Yamaguchi Masaya (Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Osaka, Japan) ,  Kawabata Shigetada (Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Osaka, Japan) ,  Terao Yutaka (Division of Microbiology and Infection Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Terao Yutaka (Research Centre for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan)
Material： Cellular Immunology  (Cell Immunol)
Volume： 325  Page： 14-22  Publication year： 2018 
JST Material Number： A0709B  ISSN： 0008-8749  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Streptococcus pneumoniae is a ...

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Thesaurus term： chaperone protein ,  macrophage ,  interleukin 6 ,  TNF ,  *Streptococcus pneumoniae ,  tandem mass spectrometry ,  pathogenicity ,  glyceraldehydephosphate dehydrogenase ,  *autolysis ,  *DNA binding protein ,  *inflammatory cytokine ,  *DNA
Semi thesaurus term： *DNA結合 ,  DnaK蛋白質 ,  *Toll様受容体4 , 【Automatic Indexing@JST】

Author keywords (7)： Streptococcus pneumoniae ,  Autolysis ,  DNA-binding protein ,  DnaK ,  EF-Tu ,  GAPDH ,  TLR4

JST classification (1)： Plant biochemistry  (EH01050J)

Terms in the title (7)： 自己分解 ,  放出 ,  肺炎球菌 ,  DNA結合蛋白質 ,  Toll様受容体4 ,  炎症誘発性サイトカイン ,  誘導