Art

J-GLOBAL ID：201802228669155216   Reference number：18A1607809

γH2AX is immunohistochemically detectable until 7 days after exposure of N-bis (2-hydroxypropyl) nitrosamine (DHPN) in rat lung carcinogenesis

γH2AXはラット肺発癌におけるN-ビス(2-ヒドロキシプロピル)ニトロソアミン(DHPN)の曝露後7日後まで免疫組織化学的に検出可能である

Author (7)： Ying Jane Tey Xin (Onco-Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan) ,  Ying Jane Tey Xin (Pengiran Anak Puteri Rashidah Sa’adatul Bolkiah, Institute of Health Sciences, Universiti Brunei Darussalam, BE1410, Gadong, Jalan Tungku Link, Brunei Darussalam) ,  Yokohira Masanao (Onco-Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan) ,  Nakano-Narusawa Yuko (Onco-Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan) ,  Yamakawa Keiko (Onco-Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan) ,  Hashimoto Nozomi (Onco-Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan) ,  Imaida Katsumi (Onco-Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan)
Material： Journal of Toxicologic Pathology (Web)  (J Toxicol Pathol (Web))
Volume： 31  Issue： 3  Page： 163-168(J-STAGE)  Publication year： 2018 
JST Material Number： U0779A  ISSN： 1881-915X  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *histone ,...
Semi thesaurus term： 発癌マーカー

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A1607809&from=J-GLOBAL&jstjournalNo=U0779A") }}

Author keywords (6)： γH2AX ,  rat ,  DHPN ,  lung ,  carcinogenesis ,  double-strand break

JST classification (2)： Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Carcinogenic mechanisms and factors  (GE02020C)

Substance index (1)： DHPN

Reference (23)：

• 1. Torre LA, Siegel RL, Ward EM, and Jemal A. Global Cancer Incidence and Mortality Rates and Trends--An Update. Cancer Epidemiol Biomarkers Prev. 25: 16-27. 2016.
• 2. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, and Bray F. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 136: E359-E386. 2015.
• 3. Torre LA, Siegel RL, and Jemal A. Lung Cancer Statistics. In: Lung Cancer and Personalized Medicine: Current Knowledge and Therapies, A Ahmad and S Gadgeel (eds). Springer International Publishing, Cham. 1-19. 2016.
• 4. Siegel RL, Miller KD, and Jemal A. Cancer Statistics, 2017. CA Cancer J Clin. 67: 7-30. 2017.
• 5. Negritto MC. Repairing Double-Strand DNA Breaks. Nature Education. 3: 26. 2010.

Terms in the title (9)： γH2AX ,  ラット ,  肺 ,  発癌 ,  ビス ,  ニトロソアミン ,  DHPN ,  曝露 ,  免疫組織化学