Art

J-GLOBAL ID：201802229709945857   Reference number：18A2141046

Central Nervous System Lymphoma Harboring the JAK2 V617F Mutation That Developed after a 20-year History of Polycythemia Vera

20年来続いている真性多血症後に発症したJAK2 V617F変異陽性の中枢神経系リンパ腫

Author (11)： Kajikawa Natsuki (Department of General Medicine, Ibaraki Prefecture Central Hospital, Japan) ,  Kajikawa Natsuki (Department of Primary Care and Medical Education, Faculty of Medicine, University of Tsukuba, Japan) ,  Seki Yoshimoto (Department of General Medicine, Ibaraki Prefecture Central Hospital, Japan) ,  Fujio Takayuki (Department of Hematology, Ibaraki Prefectural Central Hospital, Japan) ,  Okoshi Yasushi (Department of Hematology, Ibaraki Prefectural Central Hospital, Japan) ,  Okoshi Yasushi (Ibaraki Clinical Educational and Training Center, University of Tsukuba Hospital, Japan) ,  Hori Mitsuo (Department of Hematology, Ibaraki Prefectural Central Hospital, Japan) ,  Saito Hitoaki (Department of Pathology, Ibaraki Prefecture Central Hospital, Japan) ,  Iijima Tatsuo (Department of Pathology, Ibaraki Prefecture Central Hospital, Japan) ,  Kojima Hiroshi (Ibaraki Clinical Educational and Training Center, University of Tsukuba Hospital, Japan) ,  Kojima Hiroshi (Department of Clinical Oncology, Ibaraki Prefectural Central Hospital, Japan)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 57  Issue： 22  Page： 3293-3297(J-STAGE)  Publication year： 2018 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *JAK2 gene ,...

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Author keywords (4)： polycythemia vera ,  primary central nervous system lymphoma ,  B-cell lymphoma ,  JAK2 V617F mutation

JST classification (3)： Clinical oncology in general  (GE03010Y) ,  Blood cell tumors(=neoplasms)  (GK04000M) ,  Nervous system diseases  (GN03000O)

Reference (21)：

• 1. Baxter EJ, Scott LM, Campbell PJ, et al; Cancer Genome Project. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 365: 1054-1061, 2005.
• 2. James C, Ugo V, Le Couédic JP, et al. A unique clonal JAK2 mutation leading to constitutive signaling causes polycythaemia vera. Nature 434: 1144-1148, 2005.
• 3. Jones AV, Kreil S, Zoi K, et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood 106: 2162-2168, 2005.
• 4. Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 352: 1779-1790, 2005.
• 5. Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7: 387-397, 2005.

Terms in the title (6)： 真性多血症 ,  発症 ,  JAK2 ,  V617F ,  変異 ,  中枢神経系リンパ腫