Art

J-GLOBAL ID：201802230008714699   Reference number：18A1850814

Antiremodeling Effect of Xanthine Oxidase Inhibition in a Canine Model of Atrial Fibrillation

心房細動のイヌモデルにおけるキサンチンオキシダーゼ阻害の抗リモデリング効果

Author (13)： Yoshizawa Tomoharu (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Yoshizawa Tomoharu (Department of Cardiology, Yamato Municipal Hospital) ,  Niwano Shinichi (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Niwano Hiroe (Department of Education, Tamagawa University, Collage of Education) ,  Tamaki Hideaki (Department of Anatomy, Kitasato University School of Medicine) ,  Nakamura Hironori (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Igarashi Tazuru (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Oikawa Jun (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Satoh Akira (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Kishihara Jun (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Murakami Masami (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Fukaya Hidehira (Department of Cardiovascular Medicine, Kitasato University School of Medicine) ,  Ako Junya (Department of Cardiovascular Medicine, Kitasato University School of Medicine)
Material： International Heart Journal (Web)
Volume： 59  Issue： 5  Page： 1077-1085(J-STAGE)  Publication year： 2018 
JST Material Number： U1357A  ISSN： 1349-3299  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *auricular fibrillation ,...
Semi thesaurus term： イヌモデル ,...

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Author keywords (4)： Reactive oxygen species ,  Oxidative stress ,  Atrial remodeling ,  Febuxostat

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： Febuxostat

Reference (30)：

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• 2. Sagor MA, Tabassum N, Potol MA, Alam MA. Xanthine oxidase inhibitor, allopurinol, prevented oxidative stress, fibrosis, and myocardial damage in isoproterenol induced aged rats. Oxid Med Cell Longev 2015; 2015: 478039.
• 3. Katoh A, Kai H, Harada H, Niiyama H, Ikeda H. Oral administration of glucosamine improves vascular endothelial function by modulating intracellular redox state. Int Heart J 2017; 58: 926-32.
• 4. Imamura H, Yamaguchi T, Nagayama D, Saiki A, Shirai K, Tatsuno I. Resveratrol ameliorates arterial stiffness assessed by cardio-ankle vascular index in patients with type 2 diabetes mellitus. Int Heart J 2017; 58: 577-83.
• 5. Kiryu M, Niwano S, Niwano H, et al. Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model. Europace 2012; 14: 1206-14.

Terms in the title (5)： 心房細動 ,  イヌ ,  モデル ,  キサンチンオキシダーゼ阻害 ,  リモデリング