Art

J-GLOBAL ID：201802230708071200   Reference number：18A1063850

The unfolded protein response mediated by PERK is casually related to the pathogenesis of intervertebral disc degeneration

PERKにより仲介される非折畳み蛋白質応答は椎間板変性の病因に関連する【JST・京大機械翻訳】

Author (12)： Fujii Takeshi (Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan) ,  Fujita Nobuyuki (Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan) ,  Suzuki Satoshi (Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan) ,  Tsuji Takashi (Department of Orthopaedic Surgery, Fujita Health University, Aichi, Japan) ,  Takaki Takashi (Section of Electron Microscopy, Showa University, Tokyo, Japan) ,  Takaki Takashi (Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Umezawa Kazuo (Department of Molecular Target Medicine, Aichi Medical University School of Medicine, Aichi, Japan) ,  Watanabe Kota (Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan) ,  Miyamoto Takeshi (Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan) ,  Horiuchi Keisuke (Department of Orthopaedic Surgery, National Defence Medical College, Saitama, Japan) ,  Matsumoto Morio (Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan) ,  Nakamura Masaya (Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan)
Material： Journal of Orthopaedic Research
Volume： 36  Issue： 5  Page： 1334-1345  Publication year： 2018 
JST Material Number： W2653A  ISSN： 0736-0266  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Although the number of patient...

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Thesaurus term： *Proteins ,  interleukin 6 ,  *pathogenesis ,  *deconvolution ,  ER stress ,  puncture ,  human ,  patient ,  fibroblast ,  sensor ,  interleukin ,  Endoplasmic Reticulum ,  TNF alpha ,  *PERK
Semi thesaurus term： 阻害剤 , 【Automatic Indexing@JST】

Author keywords (3)： unfolded protein response ,  inflammatory cytokines ,  intervertebral disc degeneration

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (5)： PERK ,  仲介 ,  非折畳み蛋白質応答 ,  椎間板変性 ,  病因