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J-GLOBAL ID：201802231216362460   Reference number：18A1518985

Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling

最適低酸素は細胞間TGFシグナル伝達を介してヒトIPSC由来肝芽分化を調節する【JST・京大機械翻訳】

Author (18)： Ayabe Hiroaki (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Anada Takahisa (Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Kamoya Takuo (Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Sato Tomoya (Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Kimura Masaki (Division of Gastroenterology, Hepatology & Nutrition, Developmental Biology, Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA) ,  Yoshizawa Emi (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Kikuchi Shunyuu (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Ueno Yasuharu (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Sekine Keisuke (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Camp J. Gray (Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany) ,  Treutlein Barbara (Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany) ,  Ferguson Autumn (Division of Gastroenterology, Hepatology & Nutrition, Developmental Biology, Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA) ,  Suzuki Osamu (Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan) ,  Takebe Takanori (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Takebe Takanori (Division of Gastroenterology, Hepatology & Nutrition, Developmental Biology, Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA) ,  Takebe Takanori (Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA) ,  Takebe Takanori (Institute of Research, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan) ,  Taniguchi Hideki (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan)
Material： Stem Cell Reports
Volume： 11  Issue： 2  Page： 306-316  Publication year： 2018 
JST Material Number： W3132A  ISSN： 2213-6711  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Timely controlled oxygen (O<su...

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Thesaurus term： *oxygen deficiency ,  mesenchyme ,  RNA ,  hepatocyte ,  stroma cell ,  *oxygen ,  *cellular signal transduction ,  endothelium ,  pluripotent stem cell ,  RNA interference ,  *differentiation(biology) ,  *human(primates)
Semi thesaurus term： 単一細胞 ,  細胞間コミュニケーション , 【Automatic Indexing@JST】

Author keywords (7)： liver bud ,  organogenesis ,  organoid ,  oxygen ,  iPSC ,  differentiation ,  hypoxia

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (8)： 低酸素 ,  TGF ,  シグナル伝達 ,  ヒト ,  IPSC ,  芽 ,  分化 ,  調節