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J-GLOBAL ID：201802231358865677   Reference number：18A0256337

Effect of essential amino acids on enteroids: Methionine deprivation suppresses proliferation and affects differentiation in enteroid stem cells

enteroidsに及ぼす必須アミノ酸の影響:メチオニン欠乏増殖を抑制し,enteroid幹細胞における分化に影響を与える【Powered by NICT】

Author (8)： Saito Yuki (Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Iwatsuki Ken (Department of Nutritional Science and Food Safety, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Hanyu Hikaru (Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Maruyama Natsuki (Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Aihara Eitaro (Department of Molecular and Cellular Physiology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267, United States) ,  Tadaishi Miki (Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Shimizu Makoto (Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Kobayashi-Hattori Kazuo (Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 488  Issue： 1  Page： 171-176  Publication year： 2017 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： We investigated the effects of...

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Thesaurus term： repetitive sequence ,  Cell Differentiation ,  mRNA ,  *stem cell ,  Cell Proliferation ,  Fluorescence ,  Jejunum ,  *essential amino acid ,  Paneth Cells ,  Goblet Cells ,  Enteroendocrine Cells ,  leucine-rich repeat-containing G-protein-coupled receptor 5 ,  intestinal stem cell ,  Organoid ,  differentiation (biology) ,  developmental physiology ,  *nutrient ,  aliphatic amine ,  sulfide (organic) ,  aliphatic carboxylic acid ,  sulfur containing amino acid ,  primary amine

Author keywords (6)： Enteroids ,  Methionine ,  Stem cells ,  Differentiation ,  Lgr5 ,  Chromogranin A

JST classification (1)： Cell physiology in general  (EF02010S)

Substance index (1)： Methionine

Terms in the title (6)： 必須アミノ酸 ,  メチオニン ,  欠乏 ,  増殖 ,  幹細胞 ,  分化