Art

J-GLOBAL ID：201802231501118489   Reference number：18A1287971

Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer

表皮および毛包発生,ホメオスタシスおよび癌におけるHedgehogシグナル伝達経路の役割【JST・京大機械翻訳】

Author (2)： Abe Yoshinori (Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-machi, Nakahara-ku, Kawasaki 211-8533, Japan) ,  Tanaka Nobuyuki (Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-machi, Nakahara-ku, Kawasaki 211-8533, Japan)
Material： Journal of Developmental Biology (Web)
Volume： 5  Issue： 4  Page： 12  Publication year： 2017 
JST Material Number： U7216A  ISSN： 2221-3759  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The epidermis is the outermost...

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Thesaurus term： Notch receptor ,  osteogenic factor ,  Carcinogenesis ,  stem cell ,  *hair follicle ,  ovarian follicle ,  *homeostasis ,  PDGF ,  basal cell carcinoma ,  *Hedgehog signaling system ,  Organogenesis ,  Wnt Proteins ,  bulge ,  *Hedgehog Proteins ,  *signal transduction pathway
Semi thesaurus term： *伝達経路 , 【Automatic Indexing@JST】

Author keywords (7)： Hedgehog signaling ,  epidermis ,  hair follicle ,  development ,  homeostasis ,  basal cell carcinoma ,  signaling crosstalk

JST classification (2)： Cell physiology in general  (EF02010S) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (142)：

• Koster, M.I.; Roop, D.R. Mechanisms Regulating Epithelial Stratification. Annu. Rev. Cell Dev. Biol. 2007, 23, 93-113.
• Fuchs, E. Scratching the surface of skin development. Nature 2007, 445, 834-842.
• Blanpain, C.; Fuchs, E. Epidermal homeostasis: A balancing act of stem cells in the skin. Nat. Rev. Mol. Cell Biol. 2009, 10, 207-217.
• Schmidt-Ullrich, R.; Paus, R. Molecular principles of hair follicle induction and morphogenesis. BioEssays 2005, 27, 247-261.
• Epstein, E.H. Basal cell carcinomas: Attack of the hedgehog. Nat. Rev. Cancer 2008, 8, 743-754.

Terms in the title (7)： 表皮 ,  毛包 ,  ホメオスタシス ,  癌 ,  Hedgehogシグナル ,  伝達経路 ,  役割