Art

J-GLOBAL ID：201802231664456235   Reference number：18A1633054

Identification of a novel class of small compounds with anti-tuberculosis activity by in silico structure-based drug screening

in silicoでのstructure-based drug screening法による抗結核菌活性を有する低分子化合物の新たなクラスの同定

Author (10)： TAIRA Junichi (Kyushu Inst. of Technol., Iizuka, JPN) ,  MORITA Koji (Kyushu Inst. of Technol., Iizuka, JPN) ,  KAWASHIMA Shotaro (Kyushu Inst. of Technol., Iizuka, JPN) ,  UMEI Tomohiro (Kyushu Inst. of Technol., Iizuka, JPN) ,  BABA Hiroki (Kyushu Inst. of Technol., Iizuka, JPN) ,  MARUOKA Taira (Kyushu Inst. of Technol., Iizuka, JPN) ,  KOMATSU Hideyuki (Kyushu Inst. of Technol., Iizuka, JPN) ,  SAKAMOTO Hiroshi (Kyushu Inst. of Technol., Iizuka, JPN) ,  SACCHETTINI James C (Texas A&M Univ., Texas, USA) ,  AOKI Shunsuke (Kyushu Inst. of Technol., Iizuka, JPN)
Material： Journal of Antibiotics (Web)  (J Antibiot (Web))
Volume： 70  Issue： 11  Page： 1057-1064 (WEB ONLY)  Publication year： Nov. 2017 
JST Material Number： U0320A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： screening(inspection) ,...
Semi thesaurus term： drug screening ,...

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JST classification (3)： Basic research of antibacterial drugs  (GW17020S) ,  Molecular and genetic information processing  (JE15040B) ,  Physiology and pathogenicity of microbial infection  (EG03053T)

Substance index (4)： KMD6 ,  1-[(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]naphthalen-2-yl 4-methylbenzenesulfonate ,  2-bromo-4-[(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenyl 4-methoxybenzenesulfonate ,  2-methoxy-4-[(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenyl 4-methylbenzenesulfonate

Terms in the title (5)： 結核菌 ,  活性 ,  低分子化合物 ,  クラス ,  同定