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J-GLOBAL ID:201802232069983121   Reference number:18A1793699

TORC1シグナル伝達経路を介した細胞の栄養応答機構

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Volume: 132  Issue:Page: 77-82  Publication year: Mar. 10, 2018 
JST Material Number: F0877A  ISSN: 0029-0440  CODEN: NIGZAY  Document type: Article
Article type: 文献レビュー  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Cell physiology in general 
Reference (21):
  • Cornu M, Albert V and Hall MN: mTOR in aging, metabolism, and cancer. Curr Opin Genet Dev 23: 53-62, 2013.
  • Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E and Miller RA: Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460: 392-395, 2009.
  • Yang H, Jiang X, Li B, Yang HJ, Miller M, Yang A, Dhar A and Pavletich NP: Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature 552: 368-373, 2017.
  • Inoki K, Li Y, Zhu T, Wu J and Guan KL: TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4: 648-657, 2002.
  • Inoki K, Zhu T and Guan KL: TSC2 mediates cellular energy response to control cell growth and survival. Cell 115: 577-590, 2003.
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