Art

J-GLOBAL ID：201802233779348482   Reference number：18A0278061

Safety evaluation of dermal exposure to phthalates: Metabolism-dependent percutaneous absorption

フタル酸エステルへの皮膚曝露の安全性評価:代謝依存性経皮吸収【Powered by NICT】

Author (10)： Sugino Masahiro (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan) ,  Hatanaka Tomomi (Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan) ,  Todo Hiroaki (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan) ,  Mashimo Yuko (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan) ,  Suzuki Takamasa (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan) ,  Kobayashi Miho (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan) ,  Hosoya Osamu (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan) ,  Jinno Hideto (Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya 468-8503, Japan) ,  Juni Kazuhiko (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan) ,  Sugibayashi Kenji (Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan)
Material： Toxicology and Applied Pharmacology  (Toxicol Appl Pharmacol)
Volume： 328  Page： 10-17  Publication year： 2017 
JST Material Number： H0532A  ISSN： 0041-008X  CODEN： TXAPA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Phthalates, known as reproduct...

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Thesaurus term： species specificity ,  ester bond hydrolase ,  reproduction toxicity ,  *percutaneous absorption ,  endocrine disruptor ,  human ,  lipid ,  metabolite ,  polyvinyl chloride ,  plasticizer (admixture) ,  stratum corneum ,  *Metabolism ,  *epicutaneous exposure ,  *Phthalate ester ,  chemical substance
Semi thesaurus term： 透過性 , 【Automatic Indexing@JST】

Author keywords (5)： Phthalates ,  Dermal exposure ,  Skin permeation ,  Metabolism ,  Risk identification

JST classification (1)： Toxicity of organic compounds  (GZ02030Y)

Terms in the title (6)： フタル酸エステル ,  皮膚曝露 ,  安全性評価 ,  代謝 ,  依存性 ,  経皮吸収