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J-GLOBAL ID：201802234708623959   Reference number：18A0795338

Alternative pathway activation due to low level of complement factor H in primary antiphospholipid syndrome

原発性抗リン脂質抗体症候群における補体因子Hの低レベルによる代替経路活性化【JST・京大機械翻訳】

Author (14)： Nakamura Hiroyuki (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Oku Kenji (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Ogata Yusuke (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Ohmura Kazumasa (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Yoshida Yoko (Department of Blood Transfusion Medicine, Nara Medical University, Shijo-cho 840, Kashihara 634-8521, Japan) ,  Kitano Etsuko (Department of Clinical Laboratory Science, Kobe Tokiwa University, Ohtani-cho 2-6-6, Nagata-ku, Kobe 653-0838, Japan) ,  Fujieda Yuichiro (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Kato Masaru (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Bohgaki Toshiyuki (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Amengual Olga (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Yasuda Shinsuke (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Fujimura Yoshihiro (Department of Blood Transfusion Medicine, Nara Medical University, Shijo-cho 840, Kashihara 634-8521, Japan) ,  Seya Tsukasa (Department of Vaccine Immunology, Faculty of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan) ,  Atsumi Tatsuya (Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan)
Material： Thrombosis Research  (Thromb Res)
Volume： 164  Page： 63-68  Publication year： 2018 
JST Material Number： B0585B  ISSN： 0049-3848  CODEN： THBRAA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Although complement activation...

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Thesaurus term： *antiphospholipid antibody syndrome ,  connective tissue disease ,  autoantibody ,  *complement (immunology) ,  patient ,  Serum ,  cofactor ,  Western blotting ,  Proteins ,  Complement Activation ,  *antiphospholipid antibody ,  affinity ,  ELISA ,  Thrombosis ,  *Complement Factor H ,  bioassay ,  Thromboembolism

Author keywords (6)： Antiphospholipid syndrome ,  Antiphospholipid antibodies ,  Complement ,  Factor H ,  Alternative pathway ,  Thrombophilia

JST classification (1)： Immunologic diseases,allergic diseases in general.  (GD04010C)

Terms in the title (5)： 原発性抗リン脂質抗体症候群 ,  補体因子H ,  代替 ,  経路 ,  活性化