Art
J-GLOBAL ID：201802234712475969   Reference number：18A0275089

Chaperone-mediated autophagy promotes lung cancer cell survival through selective stabilization of the pro-survival protein, MCL1

シャペロン仲介オートファジーは生存促進性蛋白質,MCL1の選択的安定化を介して肺癌の細胞生存を促進する【Powered by NICT】
Author (5)：
Suzuki Junya

About Suzuki Junya

(Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan)

About Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan

, 
Nakajima Wataru

About Nakajima Wataru

(Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan)

About Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan

, 
Suzuki Hidenori

About Suzuki Hidenori

(Division of Morphological and Biomolecular Research, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan)

About Division of Morphological and Biomolecular Research, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan

, 
Asano Yumi

About Asano Yumi

(Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan)

About Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan

, 
Tanaka Nobuyuki

About Tanaka Nobuyuki

(Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan)

About Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan


Material：
Biochemical and Biophysical Research Communications  (BBRC)

About Biochemical and Biophysical Research Communications


Volume： 482  Issue： 4  Page： 1334-1340  Publication year： 2017 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
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Autophagy is a dynamic recycli...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
non-small cell lung cancer

About non-small cell lung cancer

, 
Apoptosis

About Apoptosis

, 
*lung tumor

About lung tumor

, 
proteolysis

About proteolysis

, 
homeostasis

About homeostasis

, 
Membrane Proteins

About Membrane Proteins

, 
tumor cell

About tumor cell

, 
lysosome

About lysosome

, 
molecular targeting drug

About molecular targeting drug

, 
*Proteins

About Proteins

, 
*Autophagy

About Autophagy

, 
*chaperone protein

About chaperone protein

, 
Macroautophagy

About Macroautophagy


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
阻害剤

About 阻害剤

, 【Automatic Indexing@JST】
Author keywords (6)：
Chaperone-mediated autophagy

About Chaperone-mediated autophagy

, 
Lung cancer

About Lung cancer

, 
MCL1

About MCL1

, 
Ubiquitination

About Ubiquitination

, 
Apoptosis

About Apoptosis

, 
Cancer chemotherapy

About Cancer chemotherapy

JST classification (1)：
JST classification
Category name(code) classified by JST.
Cell physiology in general 
(EF02010S)

About Cell physiology in general

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Crizotinib

About Crizotinib

Terms in the title (9)：
Terms in the title
Keywords automatically extracted from the title.
シャペロン

About シャペロン

, 
仲介

About 仲介

, 
オートファジー

About オートファジー

, 
生存

About 生存

, 
蛋白質

About 蛋白質

, 
安定化

About 安定化

, 
肺癌

About 肺癌

, 
細胞生存

About 細胞生存

, 
促進

About 促進


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