Art

J-GLOBAL ID：201802235136600716   Reference number：18A0780145

A double-blind randomized phase II dose-finding study of olanzapine 10 mg or 5 mg for the prophylaxis of emesis induced by highly emetogenic cisplatin-based chemotherapy

高催嘔吐性のシスプラチンベースの化学療法によって誘導された嘔吐の予防のための10mgあるいは5mgのオランザピンの二重盲検無作為化第II相用量設定試験

Author (16)： YANAI Takako (National Cancer Center Hospital, Tokyo, JPN) ,  IWASA Satoru (National Cancer Center Hospital, Tokyo, JPN) ,  HASHIMOTO Hironobu (National Cancer Center Hospital, Tokyo, JPN) ,  OHYANAGI Fumiyoshi (Cancer Inst. Hospital of Japanese Foundation for Cancer Res., Tokyo, JPN) ,  TAKIGUCHI Tomomi (Cancer Inst. Hospital of Japanese Foundation for Cancer Res., Tokyo, JPN) ,  TAKEDA Koji (Osaka City General Hospital, Osaka, JPN) ,  NAKAO Masahiko (Osaka City General Hospital, Osaka, JPN) ,  SAKAI Hiroshi (Saitama Cancer Center, Saitama, JPN) ,  NAKAYAMA Toshiaki (Saitama Cancer Center, Saitama, JPN) ,  MINATO Koichi (Gunma Prefectural Cancer Center, Gunma, JPN) ,  ARAI Takahiro (Gunma Prefectural Cancer Center, Gunma, JPN) ,  SUZUKI Kenichi (Cancer Inst. Hospital of Japanese Foundation for Cancer Res., Tokyo, JPN) ,  SHIMADA Yasuhiro (Kochi Health Sci. Center, Kochi, JPN) ,  NAGASHIMA Kengo (Chiba Univ., Chiba, JPN) ,  TERAKADO Hiroyuki (National Cancer Center Hospital, Tokyo, JPN) ,  YAMAMOTO Noboru (National Cancer Center Hospital, Tokyo, JPN)
Material： International Journal of Clinical Oncology  (Int J Clin Oncol)
Volume： 23  Issue： 2  Page： 382-388  Publication year： Apr. 2018 
JST Material Number： L3966A  ISSN： 1341-9625  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： chemotherapy ,...

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JST classification (1)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Substance index (1)： Olanzapine

Reference (20)：

• Basch E, Prestrud AA, Hesketh PJ et al (2011) Antiemetics: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol 29:4189-4198. doi: 10.1200/JCO.2010.34.4614
• National Comprehensive Cancer Network (2014) Antiemesis. In: NCCN clinical practice guidelines in oncology version 1. 2014. Available via the National Comprehensive Cancer Network. https://www.nccn.org/. Accessed 13 Sep 2014
• Suzuki K, Yamanaka T, Hashimoto H et al (2016) Randomized, double-blind, phase III trial of palonosetron versus granisetron in the triplet regimen for preventing chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy: TRIPLE study. Ann Oncol 27:1601-1606. doi: 10.1093/annonc/mdw220
• Bymaster FP, Calligaro DO, Falcone JF et al (1996) Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology 14:87-96. doi: 10.1016/0893-133X(94)00129-N
• Schotte A, Janssen PF, Gommeren W et al (1996) Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 124:57-73

Terms in the title (10)： 嘔吐 ,  シスプラチン ,  化学療法 ,  誘導 ,  予防 ,  オランザピン ,  二重盲検 ,  第II相 ,  用量 ,  試験