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J-GLOBAL ID：201802235155901025   Reference number：18A0958012

Mutations responsible for alcohol tolerance in the mutant of Synechococcus elongatus PCC 7942 (SY1043) obtained by single-cell screening system

単一細胞選抜システムによって得たSynechococcus elongatus PCC7942(SY1043)変異株におけるアルコール耐性に関与する変異

Author (10)： Hirokawa Yasutaka (Laboratory for Bioinformatics, Graduate School of Systems Life Sciences, Kyushu University, 804 Westwing, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Kanesaki Yu (NODAI Genome Research Center, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Arai Sayuri (Department of Biotechnology, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8603, Japan) ,  Saruta Fumiko (Laboratory for Bioinformatics, Graduate School of Systems Life Sciences, Kyushu University, 804 Westwing, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Hayashihara Kayoko (Kobe University Research Center for Inland Seas, 2746 Iwaya, Awaji, Hyogo 656-2401, Japan) ,  Murakami Akio (Kobe University Research Center for Inland Seas, 2746 Iwaya, Awaji, Hyogo 656-2401, Japan) ,  Shimizu Kazunori (Department of Biotechnology, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8603, Japan) ,  Honda Hiroyuki (Department of Biotechnology, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8603, Japan) ,  Yoshikawa Hirofumi (Department of Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan) ,  Hanai Taizo (Laboratory for Bioinformatics, Graduate School of Systems Life Sciences, Kyushu University, 804 Westwing, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 125  Issue： 5  Page： 572-577  Publication year： May. 2018 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *mutant ,...
Semi thesaurus term： *Synechococcus ,...

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Author keywords (5)： Cyanobacteria ,  Genome resequencing analysis ,  Alcohol tolerance ,  Isopropanol ,  NADP(H)

JST classification (2)： Microbial metabolite production  (FK03020A) ,  Metabolism and nutrition  (EG03054K)

Substance index (3)： 1-Butanol ,  2-Propanol ,  Ethanol

Reference (29)：

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• Foo, J. L., Jensen, H. M., Dahl, R. H., George, K., Keasling, J. D., Lee, T. S., Leong, S., and Mukhopadhyay, A.: Improving microbial biogasoline production in Escherichia coli using tolerance engineering, mBio, 5, e01932-14 (2014).
• Woodruff, L. B. A., Boyle, N. R., and Gill, R. T.: Engineering improved ethanol production in Escherichia coli with a genome-wide approach, Metab. Eng., 17, 1-11 (2013).
• Yuan, Y., Bi, C., Nicolaou, S. A., Zingaro, K. A., Ralston, M., and Papoutsaks, E.: Overexpression of the Lactobacillus plantarum peptidoglycan biosynthesis murA2 gene increases the tolerance of Escherichia coli to alcohols and enhances ethanol production, Appl. Microbiol. Biotechnol., 98, 8399-8411 (2014).

Terms in the title (6)： 単一細胞 ,  Synechococcus ,  変異株 ,  アルコール ,  耐性 ,  変異