Art

J-GLOBAL ID：201802235905927293   Reference number：18A1496108

Oral Fat Tolerance Test for Sitosterolemia and Familial Hypercholesterolemia: A Study Protocol

シトステロール血症および家族性高コレステロール血症に対する経口脂肪負荷試験:研究プロトコル

Author (6)： Nomura Akihiro (Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine) ,  Nomura Akihiro (Innovative Clinical Research Center, Kanazawa University (iCREK)) ,  Tada Hayato (Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine) ,  Nohara Atsushi (Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine) ,  Kawashiri Masa-aki (Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine) ,  Yamagishi Masakazu (Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 25  Issue： 8  Page： 741-746(J-STAGE)  Publication year： 2018 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： RLP ,...

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Author keywords (3)： Sitosterolemia ,  Familial hypercholesterolemia ,  Post-prandial hyperlipidemia

JST classification (2)： Congenital diseases,deformities in general.  (GD03010V) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Reference (27)：

• 1) Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH: Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science, 2000; 290: 1771-1775
• 2) Teupser D, Baber R, Ceglarek U, Scholz M, Illig T, Gieger C, Holdt LM, Leichtle A, Greiser KH, Huster D, Linsel-Nitschke P, Schafer A, Braund PS, Tiret L, Stark K, Raaz-Schrauder D, Fiedler GM, Wilfert W, Beutner F, Gielen S, Grosshennig A, Konig IR, Lichtner P, Heid IM, Kluttig A, El Mokhtari NE, Rubin D, Ekici AB, Reis A, Garlichs CD, Hall AS, Matthes G, Wittekind C, Hengstenberg C, Cambien F, Schreiber S, Werdan K, Meitinger T, Loeffler M, Samani NJ, Erdmann J, Wichmann HE, Schunkert H, Thiery J: Genetic regulation of serum phytosterol levels and risk of coronary artery disease. Circ Cardiovasc Genet, 2010; 3: 331-339
• 3) Silbernagel G, Chapman MJ, Genser B, Kleber ME, Fauler G, Scharnagl H, Grammer TB, Boehm BO, Makela KM, Kahonen M, Carmena R, Rietzschel ER, Bruckert E, Deanfield JE, Miettinen TA, Raitakari OT, Lehtimaki T, Marz W: High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis. J Am Coll Cardiol, 2013; 62: 291-299
• 4) Stender S, Frikke-Schmidt R, Nordestgaard BG, Tybjaerg-Hansen A: The ABCG5/8 cholesterol transporter and myocardial infarction versus gallstone disease. J Am Coll Cardiol, 2014; 63: 2121-2128
• 5) Tsubakio-Yamamoto K, Nishida M, Nakagawa-Toyama Y, Masuda D, Ohama T, Yamashita S: Current therapy for patients with sitosterolemia--effect of ezetimibe on plant sterol metabolism. J Atheroscler Thromb, 2010; 17: 891-900

Terms in the title (5)： シトステロール血症 ,  家族性高コレステロール血症 ,  脂肪負荷試験 ,  研究 ,  プロトコル