Art

J-GLOBAL ID：201802236405842392   Reference number：18A0070484

Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells

ヒト多能性幹細胞からの完全に肝芽の大量で再現可能な生成【Powered by NICT】

Author (30)： Takebe Takanori (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Takebe Takanori (Advanced Medical Research Center, Yokohama City University, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Takebe Takanori (PRESTO, Japan Science and Technology Agency, 4-1-8, Honcho, Kawaguchi, Saitama 332-0012, Japan) ,  Takebe Takanori (Division of Gastroenterology, Hepatology, and Nutrition and Developmental Biology, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA) ,  Takebe Takanori (Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA) ,  Sekine Keisuke (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Kimura Masaki (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Yoshizawa Emi (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Ayano Satoru (Molding Component Business Department, Kuraray Co., Ltd., Tsukuba 305-0841, Japan) ,  Koido Masaru (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Funayama Shizuka (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Nakanishi Noriko (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Hisai Tomoko (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Kobayashi Tatsuya (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Kasai Toshiharu (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Kitada Rina (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Mori Akira (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Ayabe Hiroaki (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Ejiri Yoko (Molding Component Business Department, Kuraray Co., Ltd., Tsukuba 305-0841, Japan) ,  Amimoto Naoki (Healios K.K, 2-4-1 Hamamatsucho, Minato-ku, Tokyo 105-6115, Japan) ,  Yamazaki Yosuke (Healios K.K, 2-4-1 Hamamatsucho, Minato-ku, Tokyo 105-6115, Japan) ,  Ogawa Shimpei (Institute for Innovation, Ajinomoto Co., Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki 210-8681, Japan) ,  Ishikawa Momotaro (Nikon Corporation, Tokyo, Japan) ,  Kiyota Yasujiro (Nikon Corporation, Tokyo, Japan) ,  Sato Yasuhiko (Carl Zeiss Microscopy Co., Ltd., Tokyo, Japan) ,  Nozawa Kohei (Sekisui Medical Co., Ltd., Tokyo, Japan) ,  Okamoto Satoshi (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Ueno Yasuharu (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Taniguchi Hideki (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Taniguchi Hideki (Advanced Medical Research Center, Yokohama City University, Kanazawa-ku, Fukuura 3-9, Yokohama, Kanagawa 236-0004, Japan)
Material： Cell Reports
Volume： 21  Issue： 10  Page： 2661-2670  Publication year： 2017 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Organoid technology provides a...

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Thesaurus term： *human ,  mesenchyme ,  *pluripotent stem cell ,  interaction ,  mass production ,  reproducibility ,  induced pluripotent stem cell ,  liver disease ,  endoderm ,  culture (biology) ,  Dyshepatia ,  diversified management ,  Organoid ,  blood vessel network ,  committed stem cell

Author keywords (9)： iPSC ,  liver bud ,  organoid ,  transplantation ,  self-organization ,  endothelial ,  mesenchymal ,  liver failure ,  clinical grade

JST classification (2)： Cell and tissue culture methods  (EA03040R) ,  Cell physiology in general  (EF02010S)

Terms in the title (3)： ヒト ,  多能性幹細胞 ,  芽