Art

J-GLOBAL ID：201802237853174284   Reference number：18A1103202

Onset of Hemophagocytic Lymphohistiocytosis during Piperacillin-Tazobactam Therapy in Three Children with Acute Focal Bacterial Nephritis

急性巣状細菌性腎炎の3小児におけるピペラシリン-タゾバクタム療法中の血球貪食症候群の発症

Author (11)： Miyabayashi Hiroki (Department of Pediatrics, Sendai Medical Center) ,  Kumaki Satoru (Department of Pediatrics, Sendai Medical Center) ,  Sato Atsushi (Department of Hematology and Oncology, Miyagi Children’s Hospital) ,  Onuma Ryoichi (Department of Pediatrics, Sendai Medical Center) ,  Noguchi Rie (Department of Pediatrics, Sendai Medical Center) ,  Sato Taiki (Department of Pediatrics, Sendai Medical Center) ,  Metoki Takaya (Department of Pediatrics, Sendai Medical Center) ,  Watanabe Yohei (Department of Pediatrics, Sendai Medical Center) ,  Tazawa Yusaku (Department of Pediatrics, Sendai Medical Center) ,  Imaizumi Masue (Department of Hematology and Oncology, Miyagi Children’s Hospital) ,  Kitaoka Setsuko (Department of Pediatrics, Sendai Medical Center)
Material： Tohoku Journal of Experimental Medicine  (Tohoku J Exp Med)
Volume： 245  Issue： 1  Page： 55-59(J-STAGE)  Publication year： 2018 
JST Material Number： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *hemophagocytic syndrome ,...

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Author keywords (5)： acute focal bacterial nephritis ,  antibiotics ,  computed tomography ,  hemophagoytic lymphohistiocytosis ,  piperacillin-tazobactam

JST classification (2)： Poisoning in general  (GD06010Q) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Substance index (1)： piperacillin/Tazobactam

Reference (22)：

• Cabañas, R., Calderon, O., Ramirez, E., Fiandor, A., Prior, N., Caballero, T., Herránz, P., Bobolea, I., López-Serrano, M.C., Quirce, S. & Bellón, T. (2014) Piperacillin-induced DRESS: distinguishing features observed in a clinical and allergy study of 8 patients. J. Investig. Allergol. Clin. Immunol., 24, 425-430.
• Cacoub, P., Musette, P., Descamps, V., Meyer, O., Speirs, C., Finzi, L. & Roujeau, J.C. (2011) The DRESS syndrome: a literature review. Am. J. Med., 124, 588-597.
• Chandrakasan, S. & Filipovich, A.H. (2013) Hemophagocytic lymphohistiocytosis: advances in pathophysiology, diagnosis, and treatment. J. Pediatr., 163, 1253-1259.
• Daubner, B., Groux-Keller, M., Hausmann, O.V., Kawabata, T., Naisbitt, D.J., Park, B.K., Wendland, T., Lerch, M. & Pichler, W.J. (2012) Multiple drug hypersensitivity: normal Treg cell function but enhanced in vivo activation of drug-specific T cells. Allergy, 67, 58-66.
• Eshki, M., Allanore, L., Musette, P., Milpied, B., Grange, A., Guillaume, J.C., Chosidow, O., Guillot, I., Paradis, V., Joly, P., Crickx, B., Ranger-Rogez, S. & Descamps, V. (2009) Twelve-year analysis of severe cases of drug reaction with eosinophilia and systemic symptoms: a cause of unpredictable multiorgan failure. Arch. Dermatol., 145, 67-72.

Terms in the title (7)： 急性巣状細菌性腎炎 ,  小児 ,  ピペラシリン ,  タゾバクタム ,  療法 ,  血球貪食症候群 ,  発症