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J-GLOBAL ID：201802237884720385   Reference number：18A2061918

Intracellular protons accelerate aging and switch on aging hallmarks in mice

細胞内プロトンはマウスにおける加齢と加齢に関するスイッチを加速する【JST・京大機械翻訳】

Author (9)： Osanai Tomohiro (Department of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Japan) ,  Tanaka Makoto (Department of Hypertension and Stroke Internal Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Izumiyama Kei (Department of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Mikami Kasumi (Department of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Japan) ,  Kitajima Maiko (Department of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Japan) ,  Tomisawa Toshiko (Department of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Japan) ,  Magota Koji (Daiichi Sankyo Co, Ltd, Biologics Technology Research Laboratories Group 1, Pharmaceutical Technology Division, Gunma, Japan) ,  Tomita Hirofumi (Department of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Okumura Ken (Saiseikai Kumamoto Hospital, Division of Cardiology, Kumamoto, Japan)
Material： Journal of Cellular Biochemistry  (J Cell Biochem)
Volume： 119  Issue： 12  Page： 9825-9837  Publication year： 2018 
JST Material Number： D0326B  ISSN： 0730-2312  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Diet-induced metabolic acidosi...

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Thesaurus term： histone ,  infection ,  methylation ,  therapy ,  serum ,  acidosis ,  autophagy ,  acetylation ,  phenotype ,  salinity ,  *proton ,  heart
Semi thesaurus term： エメリン ,  Atg7蛋白質 ,  過剰発現 , 【Automatic Indexing@JST】

Author keywords (8)： aging ,  ATP synthase ,  autophagy ,  coupling factor 6 ,  epigenetics ,  genomic instability ,  intracellular acidosis ,  salt

JST classification (3)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U) ,  Gene expression  (EC02040Q)

Terms in the title (4)： プロトン ,  マウス ,  加齢 ,  加速