Art

J-GLOBAL ID：201802239821969886   Reference number：18A0768554

Branched-chain amino acids regulate type I tropocollagen and type III tropocollagen syntheses via modulation of mTOR in the skin

分枝鎖アミノ酸は皮膚のmTORの調節を介してI型トロポコラーゲンおよびIII型トロポコラーゲン合成を調節する

Author (6)： YAMANE Takumi (Tokyo Univ. Agriculture, Tokyo, JPN) ,  MORIOKA Yuka (Tokyo Univ. Agriculture, Tokyo, JPN) ,  KITAURA Yasuyuki (Nagoya Univ., Nagoya, JPN) ,  IWATSUKI Ken (Tokyo Univ. Agriculture, Tokyo, JPN) ,  SHIMOMURA Yoshiharu (Nagoya Univ., Nagoya, JPN) ,  OISHI Yuichi (Tokyo Univ. Agriculture, Tokyo, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 82  Issue： 4  Page： 611-615  Publication year： Apr. 2018 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *branched-chain amino acid ,...
Semi thesaurus term： mTOR ,...

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JST classification (2)： Basic dermatology  (GF01020Y) ,  Metabolism and nutrition of proteins,peptides and amino acids  (EJ02032I)

Substance index (3)： Isoleucine ,  Valine ,  Leucine

Reference (24)：

• Nigel PB. Inherited diseases of collagen, elastin and keratin. Medicine. 2005;33:83-86.
• Epstein EH Jr. (Alpha1(3))3 human skin collagen. Release by pepsin digestion and preponderance in fetal life. J Biol Chem. 1974;249:3225-3231.
• Baumann L, Kaufman J, Saghari S. Collagen fillers. Dermatol Ther. 2006;19:134-140.
• Griffiths CE, Russman AN, Majmudar G, et al. Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid). N Engl J Med. 1993;329:530-535.
• Talwar HS, Griffiths CE, Fisher GJ, et al. Reduced Type I and Type III procollagens in photodamaged adult human skin. J Invest Dermatol. 1995;105:285-290.

Terms in the title (5)： 分枝鎖アミノ酸 ,  皮膚 ,  mTOR ,  調節 ,  トロポコラーゲン