Art

J-GLOBAL ID：201802243113936022   Reference number：18A0945984

Crucial role of P2X₇ receptor for effector T cell activation in experimental autoimmune uveitis

実験的自己免疫性ぶどう膜炎におけるエフェクターT細胞活性化に対するP2X₇受容体の重要な役割

Author (15)： TAKEDA Atsunobu (Kyushu Univ., Fukuoka, JPN) ,  TAKEDA Atsunobu (Kyushu Medical Center, Fukuoka, JPN) ,  YAMADA Hisakata (Kyushu Univ., Fukuoka, JPN) ,  YAMADA Hisakata (Kyushu Medical Center, Fukuoka, JPN) ,  HASEGAWA Eiichi (Kyushu Univ., Fukuoka, JPN) ,  ARIMA Mitsuru (Kyushu Univ., Fukuoka, JPN) ,  NOTOMI Shoji (Kyushu Univ., Fukuoka, JPN) ,  MYOJIN Sayaka (Kyushu Univ., Fukuoka, JPN) ,  YOSHIMURA Takeru (Kyushu Univ., Fukuoka, JPN) ,  HISATOMI Toshio (Kyushu Univ., Fukuoka, JPN) ,  ENAIDA Hiroshi (Saga Univ., Saga, JPN) ,  YANAI Ryoji (Yamaguchi Univ., Yamaguchi, JPN) ,  KIMURA Kazuhiro (Yamaguchi Univ., Yamaguchi, JPN) ,  ISHIBASHI Tatsuro (Kyushu Univ., Fukuoka, JPN) ,  SONODA Koh-Hei (Kyushu Univ., Fukuoka, JPN)
Material： Japanese Journal of Ophthalmology  (Jpn J Ophthalmol)
Volume： 62  Issue： 3  Page： 398-406  Publication year： May. 2018 
JST Material Number： G0421C  ISSN： 0021-5155  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： *P2X7 receptor ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A0945984&from=J-GLOBAL&jstjournalNo=G0421C") }}

JST classification (3)： Basic ophthalmology  (GP01020C) ,  Hormones,cytokines,bioactive peptides in general  (EB08010W) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Reference (45)：

• Kerr EC, Copland DA, Dick AD, Nicholson LB. The dynamics of leukocyte infiltration in experimental autoimmune uveoretinitis. Prog Retin Eye Res. 2008;27:527-35.
• Forrester JV. Uveitis: pathogenesis. Lancet. 1991;338:1498-501.
• Luger D, Silver PB, Tang J, Cua D, Chen Z, Iwakura Y, et al. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med. 2008;205:799-810.
• Sun B, Sun SH, Chan CC, Wiggert B, Caspi RR. Autoimmunity to a pathogenic retinal antigen begins as a balanced cytokine response that polarizes towards type 1 in a disease-susceptible and towards type 2 in a disease-resistant genotype. Int Immunol. 1999;11:1307-12.
• Takeda A, Hasegawa E, Fukuhara T, Hirakawa S, Yamada H, Yang Y, et al. EBI3 is pivotal for the initiation of experimental autoimmune uveitis. Exp Eye Res. 2014;125:107-13.

Terms in the title (7)： 実験 ,  自己免疫 ,  ぶどう膜炎 ,  エフェクターT細胞 ,  活性化 ,  P2X7受容体 ,  役割