Art
J-GLOBAL ID：201802243725096602   Reference number：18A1367014

The critical role of His48 in mouse cytosolic sulfotransferase SULT2A8 for the 7α-hydroxyl sulfation of bile acids

胆汁酸の7α-ヒドロキシル硫酸化のためのマウスサイトゾルスルホトランスフェラーゼSULT2A8におけるHis48の重要な役割
Author (5)：
SHIMOHIRA Takehiko

About SHIMOHIRA Takehiko

(Univ. Miyazaki, Miyazaki, JPN)

About Univ. Miyazaki, Miyazaki, JPN

, 
KUROGI Katsuhisa

About KUROGI Katsuhisa

(Univ. Miyazaki, Miyazaki, JPN)

About Univ. Miyazaki, Miyazaki, JPN

, 
LIU Ming-Cheh

About LIU Ming-Cheh

(Univ. Toledo Health Sci. Campus, OH, USA)

About Univ. Toledo Health Sci. Campus, OH, USA

, 
SUIKO Masahito

About SUIKO Masahito

(Univ. Miyazaki, Miyazaki, JPN)

About Univ. Miyazaki, Miyazaki, JPN

, 
SAKAKIBARA Yoichi

About SAKAKIBARA Yoichi

(Univ. Miyazaki, Miyazaki, JPN)

About Univ. Miyazaki, Miyazaki, JPN


Material：
Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)

About Bioscience, Biotechnology, and Biochemistry


Volume： 82  Issue： 8  Page： 1359-1365  Publication year： Aug. 2018 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)
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bile acid

About bile acid

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
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*Sulfotransferases

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,...
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Enzyme in general 
(EB09010D)

About Enzyme in general

,  Genetic variation 
(EC01030Y)

About Genetic variation

Substance index (2)：
Substance index
Chemical Substance indexed to the Article.
Leucine

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, 
Histidine

About Histidine

Reference (29)：
  • Lipmann F. Biological sulfate activation and transfer. Science. 1958;128:575-580.
  • Falany CN. Enzymology of human cytosolic sulfotransferases. FASEB J. 1997;11:206-216.
  • Hemmerich S, Verdugo D, Rath VL. Strategies for drug discovery by targeting sulfation pathways. Drug Discov Today. 2004;9:967-975.
  • Gamage N, Barnett A, Hempel N, et al. Human sulfotransferases and their role in chemical metabolism. Toxicol Sci. 2006;90:5-22.
  • Blanchard RL, Freimuth RR, Buck J, et al. A proposed nomenclature system for the cytosolic sulfotransferase (SULT) superfamily. Pharmacogenetics. 2004;14:199-211.
ｍore...
Terms in the title (3)：
Terms in the title
Keywords automatically extracted from the title.
胆汁酸

About 胆汁酸

, 
硫酸化

About 硫酸化

, 
役割

About 役割


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