Art

J-GLOBAL ID：201802243731668812   Reference number：18A2058029

Taurine Inhibits TRPV-Dependent Activity to Overcome Oxidative Stress in Caenorhabditis elegans

タウリンはCaenorhabditis elegansにおいてTRPV依存性活性を阻害して酸化ストレスを克服する

Author (14)： Moriuchi Masataka (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Moriuchi Masataka (Program for Leading Graduate School of “HIGO (Health Life Science: Interdisciplinary and Global Oriented) Program,” Kumamoto University) ,  Nakano Yoshio (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Nakano Yoshio (Program for Leading Graduate School of “HIGO (Health Life Science: Interdisciplinary and Global Oriented) Program,” Kumamoto University) ,  Tsurekawa Yu (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Tsurekawa Yu (Program for Leading Graduate School of “HIGO (Health Life Science: Interdisciplinary and Global Oriented) Program,” Kumamoto University) ,  Piruzyan Mariam (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Piruzyan Mariam (Program for Leading Graduate School of “HIGO (Health Life Science: Interdisciplinary and Global Oriented) Program,” Kumamoto University) ,  Matsuyama Shingo (Laboratory of Applied Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Sciences) ,  Nohara Hirofumi (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Nohara Hirofumi (Program for Leading Graduate School of “HIGO (Health Life Science: Interdisciplinary and Global Oriented) Program,” Kumamoto University) ,  Suico Mary Ann (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Shuto Tsuyoshi (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Kai Hirofumi (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University)
Material： Biological and Pharmaceutical Bulletin (Web)
Volume： 41  Issue： 11  Page： 1672-1677(J-STAGE)  Publication year： 2018 
JST Material Number： U1402A  ISSN： 1347-5215  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *ion channel ,...
Semi thesaurus term： *TRPV1 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A2058029&from=J-GLOBAL&jstjournalNo=U1402A") }}

Author keywords (8)： taurine ,  transient receptor potential vanilloid (TRPV) ,  Caenorhabditis elegans ,  oxidative stress ,  taurine ,  transient receptor potential vanilloid (TRPV) ,  Caenorhabditis elegans ,  oxidative stress

JST classification (2)： Aliphatic sulfonic acid,sulfinic acid,sulfenic acid and other compounds  (CF03160J) ,  Basic research of anti-inflammatory drugs  (GW15010T)

Substance index (3)： Taurine ,  Capsazepine ,  Capsaicin

Reference (36)：

• 1) Ripps H, Shen W. Review: Taurine: A “very essential” amino acid. Mol. Vis., 18, 2673-2686 (2012).
• 2) Ide T, Horii M, Kawashima K, Yamamoto T. Bile acid conjugation and hepatic taurine concentration in rats fed on pectin. Br. J. Nutr., 62, 539-550 (1989).
• 3) Bajor A, Tornblom H, Rudling M, Ung KA, Simren M. Increased colonic bile acid exposure: a relevant factor for symptoms and treatment in IBS. Gut, 64, 84-92 (2015).
• 4) Voss FK, Ullrich F, Munch J, Lazarow K, Lutter D, Mah N, Andrade-Navarro MA, von Kries JP, Stauber T, Jentsch TJ. Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC. Science, 344, 634-638 (2014).
• 5) Ito T, Schaffer SW, Azuma J. The potential usefulness of taurine on diabetes mellitus and its complications. Amino Acids, 42, 1529-1539 (2012).

Terms in the title (7)： タウリン ,  Caenorhabditis ,  TRPV ,  依存性 ,  活性 ,  阻害 ,  酸化ストレス