Art

J-GLOBAL ID：201802244095676606   Reference number：18A0661573

Sphingosine-1-Phosphate (S1P) Is a Feasible Biomarker in Predicting the Efficacy of Polymyxin B-Immobilized Fiber Direct Hemoperfusion (PMX-DHP) in Patients with Septic Shock

スフィンゴシン-1-リン酸(S1P)は,敗血症性ショック患者におけるポリミキシンB固定化繊維直接血液潅流(PMX-DHP)の有効性予測における実現可能なバイオマーカーである

Author (8)： Inoue Satoshi (Division of Trauma Surgery and Surgical Critical Care, Saga University Hospital) ,  Sakamoto Yuichiro (Department of Emergency Medicine, Saga University Hospital) ,  Koami Hiroyuki (Department of Emergency Medicine, Saga University Hospital) ,  Yamada C Kosuke (Department of Emergency Medicine, Saga University Hospital) ,  Nagashima Futoshi (Division of Trauma Surgery and Surgical Critical Care, Saga University Hospital) ,  Miike Toru (Department of Emergency Medicine, Saga University Hospital) ,  Iwamura Takashi (Division of Trauma Surgery and Surgical Critical Care, Saga University Hospital) ,  Obata Toru (Department of Surgery, Shiga University of Medical Science)
Material： Journal of Nippon Medical School  (日本医科大学雑誌)
Volume： 85  Issue： 1  Page： 39-46(J-STAGE)  Publication year： 2018 
JST Material Number： F0887A  ISSN： 1345-4676  CODEN： JNMSF5  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *PMX-DHP ,...

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Author keywords (5)： PMX-DHP ,  sepsis ,  septic shock ,  biomarkers ,  S1P

JST classification (1)： Treatment for infectious diseases,parasitic diseases.  (GD01030D)

Substance index (1)： Sphingosine-1-phosphate

Reference (44)：

• 1. Hall MJ, Williams SN, DeFrances CJ, Golosinskiy A: Inpatient care for septicemia or sepsis: a challenge for patients and hospitals. NCHS Data Brief 2011; 1-8.
• 2. Martin GS: Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes. Expert Rev Anti Infect Ther 2012; 10: 701-706.
• 3. Yao Z, Foster PA, Gross GJ: Monophosphoryl lipid A protects against endotoxic shock via inhibiting neutrophil infiltration and preventing disseminated intravascular coagulation. Circ Shock 1994; 43: 107-114.
• 4. Vincent JL, Opal SM, Marshall JC, Tracey KJ: Sepsis definitions: time for change. Lancet 2013; 381: 774-775.
• 5. Park SK, Shin SR, Hur M, Kim WH, Oh EA, Lee SH: The effect of early goal-directed therapy for treatment of severe sepsis or septic shock: A systemic review and meta-analysis. J Crit Care 2017; 38: 115-122.

Terms in the title (12)： スフィンゴシン-1-リン酸 ,  S1P ,  敗血症性ショック ,  患者 ,  ポリミキシンB ,  固定化 ,  繊維 ,  直接血液潅流 ,  PMX-DHP ,  有効性 ,  予測 ,  バイオマーカー