Art

J-GLOBAL ID：201802244461054076   Reference number：18A0790740

Genomic Signature of the Natural Oncolytic Herpes Simplex Virus HF10 and Its Therapeutic Role in Preclinical and Clinical Trials

自然腫瘍溶解性単純ヘルペスウイルスHF10のゲノム特徴と前臨床および臨床試験におけるその治療的役割【JST・京大機械翻訳】

Author (17)： Eissa Ibrahim Ragab (Cancer Immune Therapy Research Center, Graduate School of Medicine, Nagoya University) ,  Eissa Ibrahim Ragab (Department of Surgery II, Graduate School of Medicine, Nagoya University) ,  Eissa Ibrahim Ragab (Faculty of Science, Tanta University) ,  Naoe Yoshinori (Cancer Immune Therapy Research Center, Graduate School of Medicine, Nagoya University) ,  Bustos-Villalobos Itzel (Cancer Immune Therapy Research Center, Graduate School of Medicine, Nagoya University) ,  Ichinose Toru (Cancer Immune Therapy Research Center, Graduate School of Medicine, Nagoya University) ,  Tanaka Maki (Takara Bio Inc.) ,  Zhiwen Wu (Cancer Immune Therapy Research Center, Graduate School of Medicine, Nagoya University) ,  Zhiwen Wu (Department of Surgery II, Graduate School of Medicine, Nagoya University) ,  Mukoyama Nobuaki (Department of Otolaryngology, Graduate School of Medicine, Nagoya University) ,  Morimoto Taishi (Department of Surgery II, Graduate School of Medicine, Nagoya University) ,  Miyajima Noriyuki (Department of Transplantation and Endocrine Surgery, Graduate School of Medicine, Nagoya University) ,  Hitoki Hasegawa (Office of International Affairs, Graduate School of Medicine, Nagoya University) ,  Sumigama Seiji (Office of International Affairs, Graduate School of Medicine, Nagoya University) ,  Aleksic Branko (Office of International Affairs, Graduate School of Medicine, Nagoya University) ,  Kodera Yasuhiro (Department of Surgery II, Graduate School of Medicine, Nagoya University) ,  Kasuya Hideki (Cancer Immune Therapy Research Center, Graduate School of Medicine, Nagoya University)
Material： Frontiers in Oncology (Web)
Volume： 7  Page： 149  Publication year： 2017 
JST Material Number： U7089A  ISSN： 2234-943X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Oncolytic viruses (OVs) are op...

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Thesaurus term： phase 1 study ,  survival ratio ,  head and neck tumor ,  antigen ,  phase 2 study ,  *genome ,  *Simplexvirus ,  antitumor action ,  pancreatic tumor ,  NK cell ,  combination therapy ,  Safety ,  patient ,  tumor cell ,  *microorganism ,  *Herpesviridae ,  *animal virus
Semi thesaurus term： 癌治療 , 【Automatic Indexing@JST】

Author keywords (8)： herpes simplex oncolytic viruses ,  genomic structure ,  HF10 ,  talimogene laherparepvec ,  preclinical studies ,  combination therapy ,  clinical trials ,  future directions

JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of ear,nose,pharynx and larynx  (GQ04000E)

Terms in the title (8)： 腫瘍 ,  溶解性 ,  単純ヘルペスウイルスHF10 ,  ゲノム ,  臨床 ,  臨床試験 ,  治療 ,  役割