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J-GLOBAL ID：201802245172645395   Reference number：18A0084102

A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response

J蛋白質コシャペロンMonomerize IRE1へのBiPを動員し,小胞体ストレス応答を抑制する【Powered by NICT】

Author (7)： Amin-Wetzel Niko (Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK) ,  Saunders Reuben A. (Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK) ,  Kamphuis Maarten J. (Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK) ,  Rato Claudia (Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK) ,  Preissler Steffen (Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK) ,  Harding Heather P. (Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK) ,  Ron David (Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 171  Issue： 7  Page： 1625-1637.e13  Publication year： 2017 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： When unfolded proteins accumul...

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Thesaurus term： oligomerization ,  receptor ,  homeostasis ,  heat shock protein ,  complex(substance) ,  repressor ,  *endoplasmic reticulum ,  *protein ,  dimer ,  *ER stress
Semi thesaurus term： 蛋白質折畳み ,  *Bip ,  *IRE1 ,  *コシャペロン , 【Automatic Indexing@JST】

Author keywords (10)： Allosteric Regulation ,  Biological Feedback ,  Endoplasmic Reticulum ,  Fluorescence Resonance Energy Transfer ,  HSP70 Heat-Shock Proteins ,  Stress ,  Protein Dimerization ,  Protein Folding ,  Repressor Protein ,  Unfolded Protein Response

JST classification (3)： Cell physiology in general  (EF02010S) ,  Molecular structure  (EB03020Y) ,  Gene expression  (EC02040Q)

Terms in the title (5)： 蛋白質 ,  コシャペロン ,  IRE1 ,  BiP ,  小胞体ストレス応答