Art

J-GLOBAL ID：201802245354332593   Reference number：18A1341411

Phosphodiesterase 9 (PDE9) regulates bovine tracheal smooth muscle relaxation

ホスホジエステラーゼ9(PDE9)はウシの気管平滑筋弛緩を調節する

Author (5)： TAJIMA Tsuyoshi (Laboratory of Veterinary Pharmacology, Nippon Veterinary and Life Science University, 1-7-1 Kyounan-cho, Musashino-shi, Tokyo 180-8602, Japan) ,  SHINODA Tamami (Laboratory of Veterinary Pharmacology, Nippon Veterinary and Life Science University, 1-7-1 Kyounan-cho, Musashino-shi, Tokyo 180-8602, Japan) ,  URAKAWA Norimoto (Laboratory of Veterinary Pharmacology, Nippon Veterinary and Life Science University, 1-7-1 Kyounan-cho, Musashino-shi, Tokyo 180-8602, Japan) ,  SHIMIZU Kazumasa (Laboratory of Veterinary Pharmacology, Nippon Veterinary and Life Science University, 1-7-1 Kyounan-cho, Musashino-shi, Tokyo 180-8602, Japan) ,  KANEDA Takeharu (Laboratory of Veterinary Pharmacology, Nippon Veterinary and Life Science University, 1-7-1 Kyounan-cho, Musashino-shi, Tokyo 180-8602, Japan)
Material： Journal of Veterinary Medical Science (Web)
Volume： 80  Issue： 3  Page： 499-502(J-STAGE)  Publication year： 2018 
JST Material Number： U1094A  ISSN： 1347-7439  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *phosphodiesterase ,...
Semi thesaurus term： mRNA expression ,...

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Author keywords (4)： BAY 73-6691 ,  PDE9 ,  relaxation ,  tracheal smooth muscle

JST classification (2)： Other animal diseases  (FE02060T) ,  Enzyme physiology  (EJ02020P)

Substance index (2)： Carbachol ,  Vardenafil

Reference (21)：

• 1. Barnes, P. J. 2013. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 131: 636-645.
• 2. Beavo, J. A. 1995. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol. Rev. 75: 725-748.
• 3. Bloom, T. J. 2002. Cyclic nucleotide phosphodiesterase isozymes expressed in mouse skeletal muscle. Can. J. Physiol. Pharmacol. 80: 1132-1135.
• 4. Conti, M., Nemoz, G., Sette, C. and Vicini, E. 1995. Recent progress in understanding the hormonal regulation of phosphodiesterases. Endocr. Rev. 16: 370-389.
• 5. da Silva, F. H., Pereira, M. N., Franco-Penteado, C. F., De Nucci, G., Antunes, E. and Claudino, M. A. 2013. Phosphodiesterase-9 (PDE9) inhibition with BAY 73-6691 increases corpus cavernosum relaxations mediated by nitric oxide-cyclic GMP pathway in mice. Int. J. Impot. Res. 25: 69-73.

Terms in the title (5)： ホスホジエステラーゼ ,  ウシ ,  気管平滑筋 ,  弛緩 ,  調節