Art

J-GLOBAL ID：201802246518963733   Reference number：18A2218814

Synthetic construction of sugar-amino acid hybrid polymers involving globotriaose or lactose and evaluation of their biological activities against Shiga toxins produced by Escherichia coli O157:H7

グロボトリアオース又はラクトースを含む糖-アミノ酸ハイブリッド重合体の合成構築及び大腸菌O157:H7により生産される志賀毒素に対するそれらの生物活性の評価【JST・京大機械翻訳】

Author (12)： Matsuoka Koji (Area for Molecular Function, Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan) ,  Matsuoka Koji (Medical Innovation Research Unit (MiU), Advanced Institute of Innovative Technology (AIIT), Saitama University, Sakura, Saitama 338-8570, Japan) ,  Nishikawa Kiyotaka (Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, 1-3 Miyakotani, Tatara, Kyotanabe, Kyoto 610-0394, Japan) ,  Goshu Yusuke (Area for Molecular Function, Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan) ,  Koyama Tetsuo (Area for Molecular Function, Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan) ,  Hatano Ken (Area for Molecular Function, Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan) ,  Hatano Ken (Medical Innovation Research Unit (MiU), Advanced Institute of Innovative Technology (AIIT), Saitama University, Sakura, Saitama 338-8570, Japan) ,  Matsushita Takahiko (Area for Molecular Function, Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan) ,  Matsushita Takahiko (Medical Innovation Research Unit (MiU), Advanced Institute of Innovative Technology (AIIT), Saitama University, Sakura, Saitama 338-8570, Japan) ,  Watanabe-Takahashi Miho (Department of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, 1-3 Miyakotani, Tatara, Kyotanabe, Kyoto 610-0394, Japan) ,  Natori Yasuhiro (Department of Health Chemistry, School of Pharmacy, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan) ,  Terunuma Daiyo (Area for Molecular Function, Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan)
Material： Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)
Volume： 26  Issue： 22  Page： 5792-5803  Publication year： 2018 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Synthetic assembly of sugar mo...

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Thesaurus term： spacer ,  affinity ,  epitope ,  clustering ,  monomer ,  water solubility ,  copolymer ,  radical polymerization ,  *amino acid ,  neutralization ,  cytotoxicity ,  hexose ,  aldose ,  galactoside ,  disaccharide ,  pyranoside
Semi thesaurus term： 残基 ,  結合親和性 ,  糖重合体 , 【Automatic Indexing@JST】

Author keywords (6)： Carbohydrates ,  Amino acids ,  Globotriaose ,  Lactose ,  Radical polymerization ,  Shiga toxin

JST classification (4)： Structure-activity relationship of drugs  (GV01050B) ,  Synthesis of drugs  (GV01030F) ,  Peptides  (CF10080G) ,  Basic research of other drugs  (GW23010K)

Substance index (1)： Lactose

Terms in the title (10)： ラクトース ,  糖 ,  アミノ酸 ,  ハイブリッド重合体 ,  構築 ,  大腸菌O157 ,  H7 ,  志賀毒素 ,  生物活性 ,  評価