Art

J-GLOBAL ID：201802247330671377   Reference number：18A1871335

Replacement of mycophenolate mofetil with a JAK inhibitor, AS2553627, in combination with low-dose tacrolimus, for renal allograft rejection in non-human primates

非ヒト霊長類における腎臓同種移植拒絶のための低用量タクロリムスと併用したJAK阻害剤AS2553627によるミコフェノール酸モフェチルの補充【JST・京大機械翻訳】

Author (12)： Nakamura Koji (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Oshima Shinsuke (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Maeda Masashi (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Morio Hiroki (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Fukahori Hidehiko (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Nakanishi Tomonori (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Tsujimoto Susumu (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Hirose Jun (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Noto Takahisa (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Hamakawa Nozomu (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Inami Masamichi (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan) ,  Morokata Tatsuaki (Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan)
Material： International Immunopharmacology  (Int Immunopharmacol)
Volume： 64  Page： 201-207  Publication year： 2018 
JST Material Number： T0026B  ISSN： 1567-5769  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： In renal transplant patients, ...

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Thesaurus term： *human(primates) ,  graft ,  kidney transplantation ,  immunological rejection ,  pharmacokinetics ,  oral administration ,  monocyte ,  combination therapy ,  T cell ,  patient ,  ether ,  ketone ,  macrocyclic compound ,  nitrogen heterocyclic compound ,  oxygen heterocyclic compound ,  bridged compound ,  allyl compound ,  alicyclic alcohol ,  lactone ,  phenolic compound ,  olefin compound ,  unsaturated carboxylic acid ,  phenol ether ,  polynuclear aromatic compound ,  carboxylate(ester)
Semi thesaurus term： *阻害剤 ,  同種移植片 ,  *同種移植拒絶 , 【Automatic Indexing@JST】

Author keywords (5)： Janus kinase inhibitor ,  Mycophenolate mofetil ,  Tacrolimus ,  Non-human primate ,  Renal transplantation

JST classification (1)： Clinical application of immunotherapeutic agents and blood preparations  (GW22020O)

Substance index (2)： Tacrolimus ,  Mofetil mycophenolate

Terms in the title (10)： ヒト ,  霊長類 ,  腎臓 ,  同種移植拒絶 ,  低用量 ,  タクロリムス ,  併用 ,  JAK阻害剤 ,  ミコフェノール酸モフェチル ,  補充