Art

J-GLOBAL ID：201802248746436138   Reference number：18A2168742

Involvement of 5-HT_2A receptor hyperfunction in the anxiety-like behavior induced by doxorubicin and cyclophosphamide combination treatment in rats

ラットにおけるドキソルビシンおよびシクロホスファミド併用療法により誘発された不安様行動における5-HT_2A受容体機能亢進の関与

Author (11)： Nakamura Yuka (Department of Clinical Pharmacy, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Kitamura Yoshihisa (Department of Clinical Pharmacy, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Kitamura Yoshihisa (Department of Pharmacy, Okayama University Hospital, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Sumiyoshi Yusuke (Department of Clinical Pharmacy, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Naito Nanami (Department of Clinical Pharmacy, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Kan Shiho (Department of Clinical Pharmacy, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Ushio Soichiro (Department of Pharmacy, Okayama University Hospital, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Miyazaki Ikuko (Department of Medical Neurobiology, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Asanuma Masato (Department of Medical Neurobiology, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Sendo Toshiaki (Department of Clinical Pharmacy, Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan) ,  Sendo Toshiaki (Department of Pharmacy, Okayama University Hospital, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan)
Material： Journal of Pharmacological Sciences (Web)  (J Pharmacol Sci (Web))
Volume： 138  Issue： 3  Page： 192-197  Publication year： 2018 
JST Material Number： U0667A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： combination therapy ,...
Semi thesaurus term： Serotonin 5-HT1 Agonists ,...

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Author keywords (4)： Doxorubicin ,  Cyclophosphamide ,  5-HT_2A receptor ,  Anxiety

JST classification (4)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of psychotropic drugs  (GW03100Y) ,  Experimental treatment for tumors  (GE02040Y) ,  Basic psychiatry  (GR01020I)

Substance index (6)： 1-(2,5-Dimethoxy-4-iodophenylamino)propane ,  Cyclophosphamid ,  Tandospirone ,  Doxorubicin ,  Fluoxetine ,  Mirtazapine

Terms in the title (8)： ラット ,  ドキソルビシン ,  シクロホスファミド ,  併用療法 ,  誘発 ,  不安様行動 ,  5-HT2A受容体 ,  機能亢進