Art

J-GLOBAL ID：201802249116606092   Reference number：18A0580242

Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3

Bavachinは転写3の核因子κBおよびシグナルトランスデューサーと活性化剤の活性化を阻害することにより多発性骨髄腫細胞株のアポトーシスを誘導する【Powered by NICT】

Author (8)： Takeda Tomoya (Division of Pharmacotherapy, Kindai University School of Pharmacy, Kowakae, Higashi-Osaka, Osaka, Japan) ,  Tsubaki Masanobu (Division of Pharmacotherapy, Kindai University School of Pharmacy, Kowakae, Higashi-Osaka, Osaka, Japan) ,  Tomonari Yoshika (Division of Pharmacotherapy, Kindai University School of Pharmacy, Kowakae, Higashi-Osaka, Osaka, Japan) ,  Kawashima Keishi (Division of Pharmacotherapy, Kindai University School of Pharmacy, Kowakae, Higashi-Osaka, Osaka, Japan) ,  Itoh Tatsuki (Department of Food Science and Nutrition, Kindai University School of Agriculture, Nara, Nara, Japan) ,  Imano Motohiro (Department of Surgery, Kindai University School of Medicine, Osakasayama, Osaka, Japan) ,  Satou Takao (Department of Pathology, Kindai University School of Medicine, Osakasayama, Osaka, Japan) ,  Nishida Shozo (Division of Pharmacotherapy, Kindai University School of Pharmacy, Kowakae, Higashi-Osaka, Osaka, Japan)
Material： Biomedicine & Pharmacotherapy  (Biomedicine and Pharmacotherapy)
Volume： 100  Page： 486-494  Publication year： 2018 
JST Material Number： A0845C  ISSN： 0753-3322  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Bavachin is a phytoestrogen pu...

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Thesaurus term： medicinal plant ,  p53 protein ,  antitumor drug ,  *NF-kappaB ,  *Multiple Myeloma ,  *Apoptosis ,  cytotoxicity ,  Caspase 9 ,  Caspase 3 ,  survivin ,  STAT3 Transcription Factor ,  *Cell Line
Semi thesaurus term： 癌治療 ,  阻害剤 , 【Automatic Indexing@JST】

Author keywords (4)： Bavachin ,  Multiple myeloma (MM) ,  Nuclear factor kappa B (NF-κB) ,  Signal transducer and activator of transcription 3 (STAT3)

JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Bavachin

Terms in the title (11)： 転写 ,  核因子κB ,  シグナル ,  トランスデューサー ,  活性化剤 ,  活性化 ,  阻害 ,  多発性骨髄腫 ,  細胞株 ,  アポトーシス ,  誘導